Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration
Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic neoplasms characterized by ineffective hematopoiesis and myelodysplasia with a variable spectrum of clinical–biological features that can be used to build a prognostic estimation. This review summarizes the current most widely used...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/10/2052 |
| _version_ | 1797534611466616832 |
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| author | Tzu-Hua Chen-Liang |
| author_facet | Tzu-Hua Chen-Liang |
| author_sort | Tzu-Hua Chen-Liang |
| collection | DOAJ |
| description | Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic neoplasms characterized by ineffective hematopoiesis and myelodysplasia with a variable spectrum of clinical–biological features that can be used to build a prognostic estimation. This review summarizes the current most widely used prognostic scoring systems and gives a general view of the prognostic impact of somatic mutations in MDS patients. |
| first_indexed | 2024-03-10T11:32:59Z |
| format | Article |
| id | doaj.art-adb9c1d6bd6240d1a794071fcc1b0920 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T11:32:59Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-adb9c1d6bd6240d1a794071fcc1b09202023-11-21T19:07:53ZengMDPI AGJournal of Clinical Medicine2077-03832021-05-011010205210.3390/jcm10102052Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic IntegrationTzu-Hua Chen-Liang0Hematology and Oncology Unit, University Hospital Morales Meseguer, Marques de los Velez s/n, 30008 Murcia, SpainMyelodysplastic syndromes (MDS) are a group of clonal hematopoietic neoplasms characterized by ineffective hematopoiesis and myelodysplasia with a variable spectrum of clinical–biological features that can be used to build a prognostic estimation. This review summarizes the current most widely used prognostic scoring systems and gives a general view of the prognostic impact of somatic mutations in MDS patients.https://www.mdpi.com/2077-0383/10/10/2052prognostic impactclinical–genetic alterationsmyelodysplastic syndrome |
| spellingShingle | Tzu-Hua Chen-Liang Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration Journal of Clinical Medicine prognostic impact clinical–genetic alterations myelodysplastic syndrome |
| title | Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration |
| title_full | Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration |
| title_fullStr | Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration |
| title_full_unstemmed | Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration |
| title_short | Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration |
| title_sort | prognosis in myelodysplastic syndromes the clinical challenge of genomic integration |
| topic | prognostic impact clinical–genetic alterations myelodysplastic syndrome |
| url | https://www.mdpi.com/2077-0383/10/10/2052 |
| work_keys_str_mv | AT tzuhuachenliang prognosisinmyelodysplasticsyndromestheclinicalchallengeofgenomicintegration |