DNA damage in viscose factory workers occupationally exposed to carbon di-sulfide using buccal cell comet assay
Aim: The most important industrial use of carbon disulfide (CS2 ) has been in the fabrication of regenerated cellulose rayon by the viscose process and cellophane. CS2 leads to increased frequency of chromosomal aberrations in workers with occupational exposure to CS2 . Methods: In the present study...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Universidade Estadual de Campinas
2015-12-01
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| Series: | Brazilian Journal of Oral Sciences |
| Subjects: | |
| Online Access: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642078 |
| _version_ | 1818650669269123072 |
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| author | Pappuswamy Manikantan Vellingiri Balachandar Keshavarao Sasikala Subramanium Mohanadevi |
| author_facet | Pappuswamy Manikantan Vellingiri Balachandar Keshavarao Sasikala Subramanium Mohanadevi |
| author_sort | Pappuswamy Manikantan |
| collection | DOAJ |
| description | Aim: The most important industrial use of carbon disulfide (CS2 ) has been in the fabrication of regenerated cellulose rayon by the viscose process and cellophane. CS2 leads to increased frequency of chromosomal aberrations in workers with occupational exposure to CS2 . Methods: In the present study, the DNA damage was analyzed by using buccal cell comet assay for 30 viscose plant workers who are occupationally exposed to CS2 and 30 healthy individuals. Both groups were classified as smokers and non-smokers and only the experimental subjects were classified based on the exposure period. The data were analyzed statistically by the Student’s t-test. Results: The results of this study showed increased levels of DNA damage among viscose plant workers. Conclusion: The habit of cigarette smoking among the viscose workers had a synergistic effect on inducing DNA damage. |
| first_indexed | 2024-12-17T01:53:53Z |
| format | Article |
| id | doaj.art-adbbcb50ffac461bb1e6ba894166aef2 |
| institution | Directory Open Access Journal |
| issn | 1677-3225 |
| language | English |
| last_indexed | 2024-12-17T01:53:53Z |
| publishDate | 2015-12-01 |
| publisher | Universidade Estadual de Campinas |
| record_format | Article |
| series | Brazilian Journal of Oral Sciences |
| spelling | doaj.art-adbbcb50ffac461bb1e6ba894166aef22022-12-21T22:08:00ZengUniversidade Estadual de CampinasBrazilian Journal of Oral Sciences1677-32252015-12-018410.20396/bjos.v8i4.8642078DNA damage in viscose factory workers occupationally exposed to carbon di-sulfide using buccal cell comet assayPappuswamy Manikantan0Vellingiri Balachandar1Keshavarao Sasikala2Subramanium Mohanadevi3Bharathiar UniversityBharathiar UniversityBharathiar UniversityBharathiar UniversityAim: The most important industrial use of carbon disulfide (CS2 ) has been in the fabrication of regenerated cellulose rayon by the viscose process and cellophane. CS2 leads to increased frequency of chromosomal aberrations in workers with occupational exposure to CS2 . Methods: In the present study, the DNA damage was analyzed by using buccal cell comet assay for 30 viscose plant workers who are occupationally exposed to CS2 and 30 healthy individuals. Both groups were classified as smokers and non-smokers and only the experimental subjects were classified based on the exposure period. The data were analyzed statistically by the Student’s t-test. Results: The results of this study showed increased levels of DNA damage among viscose plant workers. Conclusion: The habit of cigarette smoking among the viscose workers had a synergistic effect on inducing DNA damage.https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642078Carbon di-sulphideDNA damageSmokingBuccal cell comet assay |
| spellingShingle | Pappuswamy Manikantan Vellingiri Balachandar Keshavarao Sasikala Subramanium Mohanadevi DNA damage in viscose factory workers occupationally exposed to carbon di-sulfide using buccal cell comet assay Brazilian Journal of Oral Sciences Carbon di-sulphide DNA damage Smoking Buccal cell comet assay |
| title | DNA damage in viscose factory workers occupationally exposed to carbon di-sulfide using buccal cell comet assay |
| title_full | DNA damage in viscose factory workers occupationally exposed to carbon di-sulfide using buccal cell comet assay |
| title_fullStr | DNA damage in viscose factory workers occupationally exposed to carbon di-sulfide using buccal cell comet assay |
| title_full_unstemmed | DNA damage in viscose factory workers occupationally exposed to carbon di-sulfide using buccal cell comet assay |
| title_short | DNA damage in viscose factory workers occupationally exposed to carbon di-sulfide using buccal cell comet assay |
| title_sort | dna damage in viscose factory workers occupationally exposed to carbon di sulfide using buccal cell comet assay |
| topic | Carbon di-sulphide DNA damage Smoking Buccal cell comet assay |
| url | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642078 |
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