Emotional stress as a cause of syncope and torsade de pointes in patients with long QT syndrome

Introduction. Long QT syndrome (LQTS) is a disorder of myocardial repolarization characterized by the prolongation of QT interval and high risk propensity of torsade de pointes (TdP) that can lead to syncope, cardiac arrest and sudden death. Episodes may be provoked by various stimuli de...

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Main Authors: Vukmirović Mihailo, Tomašević-Vukmirović Irena, Angelkov Lazar, Vukmirović Filip
Format: Article
Language:English
Published: Military Health Department, Ministry of Defance, Serbia 2015-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501502192V.pdf
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author Vukmirović Mihailo
Tomašević-Vukmirović Irena
Angelkov Lazar
Vukmirović Filip
author_facet Vukmirović Mihailo
Tomašević-Vukmirović Irena
Angelkov Lazar
Vukmirović Filip
author_sort Vukmirović Mihailo
collection DOAJ
description Introduction. Long QT syndrome (LQTS) is a disorder of myocardial repolarization characterized by the prolongation of QT interval and high risk propensity of torsade de pointes (TdP) that can lead to syncope, cardiac arrest and sudden death. Episodes may be provoked by various stimuli depending on the type of the condition. Case report. A 25- year-old famele patient was hospitalized due to syncope that occurred immediately after her solo concert, first time in her life. The patient studied solo singing and after intensive preparations the first solo concert was organized. Electrocardiography (ECG) on admission registered frequent ventricular premature beats (VES), followed by polymorphic ventricular tachycardia - TdP that degenerated into ventricular fibrilation (VF). After immediate cardioversion magnesium and beta-blockers were administered. TdP was registered again several times preceded by VES. The corrected QT interval (QTc) was 516 msec. For secondary prevention of sudden cardiac death, a cardioverter defibrillator was implanted, and beta-blockers continued. After a 1-year follow-up there were no recurrent episodes of TdP, and measured QTc was reduced to 484 msec. Conclusion. Patients with syncope following intensive emotional stress should be evaluated for malignant arrhythmias in the context of LQTS.
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spelling doaj.art-adbd5c3bef084416b0f95449c533749a2022-12-22T03:16:29ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502015-01-0172219219510.2298/VSP1502192V0042-84501502192VEmotional stress as a cause of syncope and torsade de pointes in patients with long QT syndromeVukmirović Mihailo0Tomašević-Vukmirović Irena1Angelkov Lazar2Vukmirović Filip3Clinical Center of Montenegro, Center of Cardiology, Podgorica, MontenegroClinical Center of Montenegro, Center of Radiology, Podgorica, MontenegroInstitute of Cardiovascular Disease Dedinje, Belgrade SerbiaClinical Center of Montenegro, Center of Patology, Podgorica, MontenegroIntroduction. Long QT syndrome (LQTS) is a disorder of myocardial repolarization characterized by the prolongation of QT interval and high risk propensity of torsade de pointes (TdP) that can lead to syncope, cardiac arrest and sudden death. Episodes may be provoked by various stimuli depending on the type of the condition. Case report. A 25- year-old famele patient was hospitalized due to syncope that occurred immediately after her solo concert, first time in her life. The patient studied solo singing and after intensive preparations the first solo concert was organized. Electrocardiography (ECG) on admission registered frequent ventricular premature beats (VES), followed by polymorphic ventricular tachycardia - TdP that degenerated into ventricular fibrilation (VF). After immediate cardioversion magnesium and beta-blockers were administered. TdP was registered again several times preceded by VES. The corrected QT interval (QTc) was 516 msec. For secondary prevention of sudden cardiac death, a cardioverter defibrillator was implanted, and beta-blockers continued. After a 1-year follow-up there were no recurrent episodes of TdP, and measured QTc was reduced to 484 msec. Conclusion. Patients with syncope following intensive emotional stress should be evaluated for malignant arrhythmias in the context of LQTS.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501502192V.pdfsyncopestress, psychologicaltorasades de pointesdrug therapyelectrophysiologic techniques, cardiac
spellingShingle Vukmirović Mihailo
Tomašević-Vukmirović Irena
Angelkov Lazar
Vukmirović Filip
Emotional stress as a cause of syncope and torsade de pointes in patients with long QT syndrome
Vojnosanitetski Pregled
syncope
stress, psychological
torasades de pointes
drug therapy
electrophysiologic techniques, cardiac
title Emotional stress as a cause of syncope and torsade de pointes in patients with long QT syndrome
title_full Emotional stress as a cause of syncope and torsade de pointes in patients with long QT syndrome
title_fullStr Emotional stress as a cause of syncope and torsade de pointes in patients with long QT syndrome
title_full_unstemmed Emotional stress as a cause of syncope and torsade de pointes in patients with long QT syndrome
title_short Emotional stress as a cause of syncope and torsade de pointes in patients with long QT syndrome
title_sort emotional stress as a cause of syncope and torsade de pointes in patients with long qt syndrome
topic syncope
stress, psychological
torasades de pointes
drug therapy
electrophysiologic techniques, cardiac
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501502192V.pdf
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