Research progress of ocular manifestations and pathological mechanisms in Alport syndrome
Alport syndrome(AS)is a genetic disease characterized by abnormal basement membrane structure of the kidneys, ears and eyes. The incidence of the disease is 1:5000 approximately. The report on ocular manifestations is relatively scarce, however, it is of great value to diagnosis of the disease. The...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2019-03-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://ies.ijo.cn/cn_publish/2019/3/201903014.pdf |
| _version_ | 1818559787495849984 |
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| author | Ye-Ting Lin |
| author_facet | Ye-Ting Lin |
| author_sort | Ye-Ting Lin |
| collection | DOAJ |
| description | Alport syndrome(AS)is a genetic disease characterized by abnormal basement membrane structure of the kidneys, ears and eyes. The incidence of the disease is 1:5000 approximately. The report on ocular manifestations is relatively scarce, however, it is of great value to diagnosis of the disease. The ocular tissue histopathological analysis provides an effective method to uncover the pathological mechanisms of AS. Besides, it is good for understanding and treatment of AS. |
| first_indexed | 2024-12-14T00:30:04Z |
| format | Article |
| id | doaj.art-adbd93bb60574ce48253c86f031a9404 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-14T00:30:04Z |
| publishDate | 2019-03-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-adbd93bb60574ce48253c86f031a94042022-12-21T23:24:54ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232019-03-0119340941310.3980/j.issn.1672-5123.2019.3.14Research progress of ocular manifestations and pathological mechanisms in Alport syndromeYe-Ting Lin0Department of Ophthalmology, Tianjin Children's Hospital,Tianjin 300000, ChinaAlport syndrome(AS)is a genetic disease characterized by abnormal basement membrane structure of the kidneys, ears and eyes. The incidence of the disease is 1:5000 approximately. The report on ocular manifestations is relatively scarce, however, it is of great value to diagnosis of the disease. The ocular tissue histopathological analysis provides an effective method to uncover the pathological mechanisms of AS. Besides, it is good for understanding and treatment of AS.http://ies.ijo.cn/cn_publish/2019/3/201903014.pdfAlport syndromeocular manifestationspathological mechanismsgene mutationbasal membrane |
| spellingShingle | Ye-Ting Lin Research progress of ocular manifestations and pathological mechanisms in Alport syndrome Guoji Yanke Zazhi Alport syndrome ocular manifestations pathological mechanisms gene mutation basal membrane |
| title | Research progress of ocular manifestations and pathological mechanisms in Alport syndrome |
| title_full | Research progress of ocular manifestations and pathological mechanisms in Alport syndrome |
| title_fullStr | Research progress of ocular manifestations and pathological mechanisms in Alport syndrome |
| title_full_unstemmed | Research progress of ocular manifestations and pathological mechanisms in Alport syndrome |
| title_short | Research progress of ocular manifestations and pathological mechanisms in Alport syndrome |
| title_sort | research progress of ocular manifestations and pathological mechanisms in alport syndrome |
| topic | Alport syndrome ocular manifestations pathological mechanisms gene mutation basal membrane |
| url | http://ies.ijo.cn/cn_publish/2019/3/201903014.pdf |
| work_keys_str_mv | AT yetinglin researchprogressofocularmanifestationsandpathologicalmechanismsinalportsyndrome |