Toward a Microencapsulated 3D hiPSC-Derived in vitro Cardiac Microtissue for Recapitulation of Human Heart Microenvironment Features

Toward a Microencapsulated 3D hiPSC-Derived in vitro Cardiac Microtissue for Recapitulation of Human Heart Microenvironment Features

The combination of cardiomyocytes (CM) and non-myocyte cardiac populations, such as endothelial cells (EC), and mesenchymal cells (MC), has been shown to be critical for recapitulation of the human heart tissue for in vitro cell-based modeling. However, most of the current engineered cardiac microti...

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Bibliographic Details
Main Authors: Bernardo Abecasis, Pedro G.M. Canhão, Henrique V. Almeida, Tomás Calmeiro, Elvira Fortunato, Patrícia Gomes-Alves, Margarida Serra, Paula M. Alves
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
hiPSC
cardiomyocytes
endothelial cells
fibroblasts
engineered cardiac tissues
microencapsulation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.580744/full

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