CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells

CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells

Objective. Activation of toll-like receptor 9 (TLR9) has been proposed to play an inhibitory role in RANKL-induced osteoclastogenesis. A20 deubiquitinase has been found to be related to bone loss. This study investigated the role of CpG oligodeoxynucleotides (CpG-ODNs) through regulation of A20 deub...

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Bibliographic Details
Main Authors:	Seong-Kyu Kim, Jung-Yoon Choe, Ki-Yeun Park
Format:	Article
Language:	English
Published:	Hindawi Limited 2022-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2022/5255935

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