Solubilization and thermodynamic properties of simvastatin in various micellar solutions of different non-ionic surfactants: Computational modeling and solubilization capacity.

Solubilization and thermodynamic properties of simvastatin in various micellar solutions of different non-ionic surfactants: Computational modeling and solubilization capacity.

The aim of this work was to solubilize simvastatin (SIM) using different micellar solutions of various non-ionic surfactants such as Tween-80 (T80), Tween-20 (T20), Myrj-52 (M52), Myrj-59 (M59), Brij-35 (B35) and Brij-58 (B58). The solubility of SIM in water (H2O) and different micellar concentratio...

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Detalhes bibliográficos
Principais autores: Faiyaz Shakeel, Sultan Alshehri, Mohamed A Ibrahim, Mohammad Altamimi, Nazrul Haq, Ehab M Elzayat, Gamal A Shazly
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2021-01-01
coleção:PLoS ONE
Acesso em linha:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0249485&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0249485&type=printable

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