Fatty acid composition and metabolic partitioning of α-linolenic acid are contingent on life stage in human CD3+ T lymphocytes

IntroductionImmune function changes across the life course; the fetal immune system is characterised by tolerance while that of seniors is less able to respond effectively to antigens and is more pro-inflammatory than in younger adults. Lipids are involved centrally in immune function but there is l...

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Bibliographic Details
Main Authors: Annette L. West, Johanna von Gerichten, Nicola A. Irvine, Elizabeth A. Miles, Karen A. Lillycrop, Philip C. Calder, Barbara A. Fielding, Graham C. Burdge
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1079642/full

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