The Generalized DUS Transformed Log-Normal Distribution and Its Applications to Cancer and Heart Transplant Datasets

Many studies have underlined the importance of the log-normal distribution in the modeling of phenomena occurring in biology. With this in mind, in this article we offer a new and motivated transformed version of the log-normal distribution, primarily for use with biological data. The hazard rate fu...

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Main Authors: Muhammed Rasheed Irshad, Christophe Chesneau, Soman Latha Nitin, Damodaran Santhamani Shibu, Radhakumari Maya
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Mathematics
Subjects:
Online Access:https://www.mdpi.com/2227-7390/9/23/3113
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author Muhammed Rasheed Irshad
Christophe Chesneau
Soman Latha Nitin
Damodaran Santhamani Shibu
Radhakumari Maya
author_facet Muhammed Rasheed Irshad
Christophe Chesneau
Soman Latha Nitin
Damodaran Santhamani Shibu
Radhakumari Maya
author_sort Muhammed Rasheed Irshad
collection DOAJ
description Many studies have underlined the importance of the log-normal distribution in the modeling of phenomena occurring in biology. With this in mind, in this article we offer a new and motivated transformed version of the log-normal distribution, primarily for use with biological data. The hazard rate function, quantile function, and several other significant aspects of the new distribution are investigated. In particular, we show that the hazard rate function has increasing, decreasing, bathtub, and upside-down bathtub shapes. The maximum likelihood and Bayesian techniques are both used to estimate unknown parameters. Based on the proposed distribution, we also present a parametric regression model and a Bayesian regression approach. As an assessment of the longstanding performance, simulation studies based on maximum likelihood and Bayesian techniques of estimation procedures are also conducted. Two real datasets are used to demonstrate the applicability of the new distribution. The efficiency of the third parameter in the new model is tested by utilizing the likelihood ratio test. Furthermore, the parametric bootstrap approach is used to determine the effectiveness of the suggested model for the datasets.
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spelling doaj.art-adc8e5660fe141a884d0a1841dfcdffb2023-11-23T02:46:14ZengMDPI AGMathematics2227-73902021-12-01923311310.3390/math9233113The Generalized DUS Transformed Log-Normal Distribution and Its Applications to Cancer and Heart Transplant DatasetsMuhammed Rasheed Irshad0Christophe Chesneau1Soman Latha Nitin2Damodaran Santhamani Shibu3Radhakumari Maya4Department of Statistics, Cochin University of Science and Technology, Cochin 682 022, Kerala, IndiaDepartment of Mathematics, Université de Caen Basse-Normandie, LMNO, UFR de Sciences, F-14032 Caen, FranceDepartment of Statistics, University College, Thiruvananthapuram 695 034, Kerala, IndiaDepartment of Statistics, University College, Thiruvananthapuram 695 034, Kerala, IndiaDepartment of Statistics, Government College for Women, Thiruvananthapuram 695 014, Kerala, IndiaMany studies have underlined the importance of the log-normal distribution in the modeling of phenomena occurring in biology. With this in mind, in this article we offer a new and motivated transformed version of the log-normal distribution, primarily for use with biological data. The hazard rate function, quantile function, and several other significant aspects of the new distribution are investigated. In particular, we show that the hazard rate function has increasing, decreasing, bathtub, and upside-down bathtub shapes. The maximum likelihood and Bayesian techniques are both used to estimate unknown parameters. Based on the proposed distribution, we also present a parametric regression model and a Bayesian regression approach. As an assessment of the longstanding performance, simulation studies based on maximum likelihood and Bayesian techniques of estimation procedures are also conducted. Two real datasets are used to demonstrate the applicability of the new distribution. The efficiency of the third parameter in the new model is tested by utilizing the likelihood ratio test. Furthermore, the parametric bootstrap approach is used to determine the effectiveness of the suggested model for the datasets.https://www.mdpi.com/2227-7390/9/23/3113log-normal distributionDUS transformationmaximum likelihood estimationBayesian estimationregression
spellingShingle Muhammed Rasheed Irshad
Christophe Chesneau
Soman Latha Nitin
Damodaran Santhamani Shibu
Radhakumari Maya
The Generalized DUS Transformed Log-Normal Distribution and Its Applications to Cancer and Heart Transplant Datasets
Mathematics
log-normal distribution
DUS transformation
maximum likelihood estimation
Bayesian estimation
regression
title The Generalized DUS Transformed Log-Normal Distribution and Its Applications to Cancer and Heart Transplant Datasets
title_full The Generalized DUS Transformed Log-Normal Distribution and Its Applications to Cancer and Heart Transplant Datasets
title_fullStr The Generalized DUS Transformed Log-Normal Distribution and Its Applications to Cancer and Heart Transplant Datasets
title_full_unstemmed The Generalized DUS Transformed Log-Normal Distribution and Its Applications to Cancer and Heart Transplant Datasets
title_short The Generalized DUS Transformed Log-Normal Distribution and Its Applications to Cancer and Heart Transplant Datasets
title_sort generalized dus transformed log normal distribution and its applications to cancer and heart transplant datasets
topic log-normal distribution
DUS transformation
maximum likelihood estimation
Bayesian estimation
regression
url https://www.mdpi.com/2227-7390/9/23/3113
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