CEND1 and NEUROGENIN2 Reprogram Mouse Astrocytes and Embryonic Fibroblasts to Induced Neural Precursors and Differentiated Neurons

CEND1 and NEUROGENIN2 Reprogram Mouse Astrocytes and Embryonic Fibroblasts to Induced Neural Precursors and Differentiated Neurons

Recent studies demonstrate that astroglia from non-neurogenic brain regions can be reprogrammed into functional neurons through forced expression of neurogenic factors. Here we explored the effect of CEND1 and NEUROG2 on reprogramming of mouse cortical astrocytes and embryonic fibroblasts. Forced ex...

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Bibliographic Details
Main Authors: Katerina Aravantinou-Fatorou, Felipe Ortega, Dafni Chroni-Tzartou, Nasia Antoniou, Cornelia Poulopoulou, Panagiotis K. Politis, Benedikt Berninger, Rebecca Matsas, Dimitra Thomaidou
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115002180

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