| Summary: | Background As individuals are increasingly attending health and wellness courses outside of the conventional medical system, there is a need to obtain objective data on the effects of those programs on well-being. Methods In total, 154 men and women (mean age 54.7 years; range 25–83) participated in 3 different holistic wellness programs based on Ayurvedic Medicine principles (Seduction of Spirit, Journey into Healing, and Perfect Health) or a vacation control group. Psychosocial outcomes included spirituality (Delaney Spirituality Scale), mindful awareness (Mindful Attention Awareness Scale), psychological flexibility (Acceptance and Action Questionnaire), mood (Center for Epidemiology Studies-Depression), and anxiety (Patient-Reported Outcomes Measurement System Anxiety Scale). Results Participants in the Seduction of Spirit ( P < .004), Journey into Healing ( P < .05), and Perfect Health ( P < .004) courses showed significant increases in spirituality as compared to vacation controls. Participants in Seduction of Spirit ( P < .007) also showed significant increases in mindfulness as compared to vacation controls. Participants in the Seduction of Spirit ( P < .001) and Journey into Healing ( P < .05) courses showed significant decreases in depressed mood as compared to those in the Perfect Health and vacation control groups. All study participants showed similar increases in psychological flexibility ( P < .01) and decreases in anxiety ( P < .01). Conclusion Participation in wellness courses that incorporate a mind–body–spirit approach to health improves multiple domains of psychosocial well-being, which persists even after course participation.
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