Platinum-Based Regimens Are Active in Advanced Pediatric-Type Rhabdomyosarcoma in Adults and Depending on HMGB1 Expression

Platinum-Based Regimens Are Active in Advanced Pediatric-Type Rhabdomyosarcoma in Adults and Depending on HMGB1 Expression

Rhabdomyosarcoma (RMS) in adults is a rare and aggressive disease, which lacks standard therapies for relapsed or advanced disease. This retrospective study aimed to describe the activity of BOMP-EPI (bleomycin, vincristine, methotrexate and cisplatin alternating with etoposide, cisplatin and ifosfa...

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Bibliographic Details
Main Authors: Nadia Hindi, Jaime Carrillo-García, Elena Blanco-Alcaina, Marta Renshaw, Pablo Luna, José Durán, Natalia Jiménez, Pilar Sancho, Rafael Ramos, David S. Moura, Javier Martín-Broto
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
rhabdomyosarcoma
BOMP-EPI
cisplatin
HMGB1
HMGB2
HMGA2
Online Access:https://www.mdpi.com/1422-0067/24/1/856

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