Successful thrombolysis in acute coronary syndrome

We report the case of a male aged by 50 years-old without medical history who consult in emergency for a prolonged constrictive thoracic left pain who irradiate to the left shoulder from 5 hours. Cardiologic and general examination were normal. In front of that we perform an ECG, who show a reciproc...

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Main Authors: Najlaa Salmi, Safae Hilal
Format: Article
Language:English
Published: PAMJ 2020-05-01
Series:PAMJ Clinical Medicine
Subjects:
Online Access: https://www.clinical-medicine.panafrican-med-journal.com/content/article/3/23/pdf/23.pdf
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author Najlaa Salmi
Safae Hilal
author_facet Najlaa Salmi
Safae Hilal
author_sort Najlaa Salmi
collection DOAJ
description We report the case of a male aged by 50 years-old without medical history who consult in emergency for a prolonged constrictive thoracic left pain who irradiate to the left shoulder from 5 hours. Cardiologic and general examination were normal. In front of that we perform an ECG, who show a reciprocal ST-segment elevation at the inferior territory (DII, DIII, aVF), on anterior and lateral derivations (A). After the elimination of thrombolysis contraindications, we administrate first a loading dose of clopidogrel, aspirin, and enoxaparin followed by tenecteplase at 0.6. The immediate follow-up was marked by the resolution of the pain and a complete resolution of the ST-segment elevation synonym of the successful thrombolysis (B). Thrombolysis is a medical technique intended to urgently dissolve a curd that blurs a coronary artery in myocardial infarction or a cerebral artery in a stroke who success only in 15% of cases. Thrombolysis show its effectiveness in terms of survival and improvement of left ventricular function. It´s indicated if the chest pain dates from less than 12 hours in the absence of contraindications. its prescription methods consist of a single intravenous bolus injection, dosage depending on weight associated with treatment with aspirin, clopidogrel and effective anticoagulation. the success criteria are clinically: pain sedation after an initial increase possible, biologically an early peak in markers of myocardial necrosis, electrically ventricular reperfusion arrhythmia (ESV, TV, RIVA) and the marked regression see the disappearance of the ST segment elevation.
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spelling doaj.art-addc41c98c784a83bbbd9d88f1fc63722022-12-21T22:11:27ZengPAMJPAMJ Clinical Medicine2707-27972707-27972020-05-0132310.11604/pamj-cm.2020.3.23.2335123351Successful thrombolysis in acute coronary syndromeNajlaa Salmi0Safae Hilal1 Cardiology Department of the Military Hospital of Instruction Mohamed V of Rabat, Rabat, Morocco Cardiology Department of the Military Hospital of Instruction Mohamed V of Rabat, Rabat, Morocco We report the case of a male aged by 50 years-old without medical history who consult in emergency for a prolonged constrictive thoracic left pain who irradiate to the left shoulder from 5 hours. Cardiologic and general examination were normal. In front of that we perform an ECG, who show a reciprocal ST-segment elevation at the inferior territory (DII, DIII, aVF), on anterior and lateral derivations (A). After the elimination of thrombolysis contraindications, we administrate first a loading dose of clopidogrel, aspirin, and enoxaparin followed by tenecteplase at 0.6. The immediate follow-up was marked by the resolution of the pain and a complete resolution of the ST-segment elevation synonym of the successful thrombolysis (B). Thrombolysis is a medical technique intended to urgently dissolve a curd that blurs a coronary artery in myocardial infarction or a cerebral artery in a stroke who success only in 15% of cases. Thrombolysis show its effectiveness in terms of survival and improvement of left ventricular function. It´s indicated if the chest pain dates from less than 12 hours in the absence of contraindications. its prescription methods consist of a single intravenous bolus injection, dosage depending on weight associated with treatment with aspirin, clopidogrel and effective anticoagulation. the success criteria are clinically: pain sedation after an initial increase possible, biologically an early peak in markers of myocardial necrosis, electrically ventricular reperfusion arrhythmia (ESV, TV, RIVA) and the marked regression see the disappearance of the ST segment elevation. https://www.clinical-medicine.panafrican-med-journal.com/content/article/3/23/pdf/23.pdf acute coronary syndromethrombolysisecg
spellingShingle Najlaa Salmi
Safae Hilal
Successful thrombolysis in acute coronary syndrome
PAMJ Clinical Medicine
acute coronary syndrome
thrombolysis
ecg
title Successful thrombolysis in acute coronary syndrome
title_full Successful thrombolysis in acute coronary syndrome
title_fullStr Successful thrombolysis in acute coronary syndrome
title_full_unstemmed Successful thrombolysis in acute coronary syndrome
title_short Successful thrombolysis in acute coronary syndrome
title_sort successful thrombolysis in acute coronary syndrome
topic acute coronary syndrome
thrombolysis
ecg
url https://www.clinical-medicine.panafrican-med-journal.com/content/article/3/23/pdf/23.pdf
work_keys_str_mv AT najlaasalmi successfulthrombolysisinacutecoronarysyndrome
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