<sup>13</sup>C-NMR Chemical Shifts in 1,3-Benzazoles as a Tautomeric Ratio Criterion

<sup>13</sup>C-NMR Chemical Shifts in 1,3-Benzazoles as a Tautomeric Ratio Criterion

Benzimidazole is an important heterocyclic fragment, present in many biologically active compounds with a great variety of therapeutic purposes. Most of the benzimidazole activities are explained through the existence of 1,3-tautomeric equilibrium. As the binding affinity of each tautomer to a prote...

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Bibliographic Details
Main Authors: Efrén V. García-Báez, Itzia I. Padilla-Martínez, Alejandro Cruz, Martha C. Rosales-Hernández
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
benzimidazoles
<sup>13</sup>C NMR
tautomeric equilibrium
mesomery
pyridine nitrogen atom
pyrrole nitrogen atom
Online Access:https://www.mdpi.com/1420-3049/27/19/6268

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