p53 Signaling on Microenvironment and Its Contribution to Tissue Chemoresistance

p53 Signaling on Microenvironment and Its Contribution to Tissue Chemoresistance

Chemoresistance persists as a significant, unresolved clinical challenge in many cancer types. The tumor microenvironment, in which cancer cells reside and interact with non-cancer cells and tissue structures, has a known role in promoting every aspect of tumor progression, including chemoresistance...

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Bibliographic Details
Main Authors: Leonel Cardozo de Menezes e Souza, Anderson Faletti, Carla Pires Veríssimo, Mariana Paranhos Stelling, Helena Lobo Borges
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Membranes
Subjects:
tumor microenvironment
p53 signaling
secretome
extracellular vesicles
drug resistance
mutant p53
Online Access:https://www.mdpi.com/2077-0375/12/2/202

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