Preparation and Properties of Chitosan Salicylaldehyde Hydrogel Loaded with Anthocyanins
In the presence of blueberry anthocyanins (ACNs), chitosan hydrogel crosslinking with salicylaldehyde (ACNs/CS-SA) was constructed. The structure and morphology of ACNs/CS-SA were characterized. The stability, swelling properties and ACNs controlled-release behaviors for the ACNs/CS-SA were investig...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | zho |
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The editorial department of Science and Technology of Food Industry
2023-05-01
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| Series: | Shipin gongye ke-ji |
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| Online Access: | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022060293 |
| _version_ | 1797737799968882688 |
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| author | Xu LI Cuifang DONG Changxia LIU Hanyue LING Ying LI Xiaozhen FAN |
| author_facet | Xu LI Cuifang DONG Changxia LIU Hanyue LING Ying LI Xiaozhen FAN |
| author_sort | Xu LI |
| collection | DOAJ |
| description | In the presence of blueberry anthocyanins (ACNs), chitosan hydrogel crosslinking with salicylaldehyde (ACNs/CS-SA) was constructed. The structure and morphology of ACNs/CS-SA were characterized. The stability, swelling properties and ACNs controlled-release behaviors for the ACNs/CS-SA were investigated in the media of different pH. ACNs were uniformly dispersed in three-dimensional network structure of CS-SA hydrogel by physical embedding, which was confirmed by FT-IR and XRD characterization. The thermal stability of ACNs was significantly improved due to gelation, which was confirmed by TG-DTG characterization. Both the swelling properties and ACNs controlled-release behaviors for the ACNs/CS-SA exhibited pH response. In buffer media of pH2.7, 4.6 and 6.7, the cumulative release rates of ACNs for 24 h were 74.28%±4.58%, 40.72%±4.04% and 15.70%±1.71%, and the release process followed Weibull equation with the correlation coefficients R2 0.99405, 0.95165 and 0.99712, respectively. This study lays a theoretical and experimental foundation for the development of novel drug encapsulation materials and the application of ACNs owing to the ACNs/CS-SA pH responsiveness and ACNs thermal stability improvement. |
| first_indexed | 2024-03-12T13:33:34Z |
| format | Article |
| id | doaj.art-ade48f2f2a0b4c24b56e53dee291c6aa |
| institution | Directory Open Access Journal |
| issn | 1002-0306 |
| language | zho |
| last_indexed | 2024-03-12T13:33:34Z |
| publishDate | 2023-05-01 |
| publisher | The editorial department of Science and Technology of Food Industry |
| record_format | Article |
| series | Shipin gongye ke-ji |
| spelling | doaj.art-ade48f2f2a0b4c24b56e53dee291c6aa2023-08-24T06:01:46ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062023-05-0144911111810.13386/j.issn1002-0306.20220602932022060293-9Preparation and Properties of Chitosan Salicylaldehyde Hydrogel Loaded with AnthocyaninsXu LI0Cuifang DONG1Changxia LIU2Hanyue LING3Ying LI4Xiaozhen FAN5Department of Chemistry and Chemical Engineering, Cangzhou Normal University, Cangzhou 061000, ChinaDepartment of Chemistry and Chemical Engineering, Cangzhou Normal University, Cangzhou 061000, ChinaDepartment of Chemistry and Chemical Engineering, Cangzhou Normal University, Cangzhou 061000, ChinaDepartment of Chemistry and Chemical Engineering, Cangzhou Normal University, Cangzhou 061000, ChinaDepartment of Chemistry and Chemical Engineering, Cangzhou Normal University, Cangzhou 061000, ChinaDepartment of Chemistry and Chemical Engineering, Cangzhou Normal University, Cangzhou 061000, ChinaIn the presence of blueberry anthocyanins (ACNs), chitosan hydrogel crosslinking with salicylaldehyde (ACNs/CS-SA) was constructed. The structure and morphology of ACNs/CS-SA were characterized. The stability, swelling properties and ACNs controlled-release behaviors for the ACNs/CS-SA were investigated in the media of different pH. ACNs were uniformly dispersed in three-dimensional network structure of CS-SA hydrogel by physical embedding, which was confirmed by FT-IR and XRD characterization. The thermal stability of ACNs was significantly improved due to gelation, which was confirmed by TG-DTG characterization. Both the swelling properties and ACNs controlled-release behaviors for the ACNs/CS-SA exhibited pH response. In buffer media of pH2.7, 4.6 and 6.7, the cumulative release rates of ACNs for 24 h were 74.28%±4.58%, 40.72%±4.04% and 15.70%±1.71%, and the release process followed Weibull equation with the correlation coefficients R2 0.99405, 0.95165 and 0.99712, respectively. This study lays a theoretical and experimental foundation for the development of novel drug encapsulation materials and the application of ACNs owing to the ACNs/CS-SA pH responsiveness and ACNs thermal stability improvement.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022060293anthocyaninschitosan hydrogelstabilityph responsesustained release propertiesdynamics |
| spellingShingle | Xu LI Cuifang DONG Changxia LIU Hanyue LING Ying LI Xiaozhen FAN Preparation and Properties of Chitosan Salicylaldehyde Hydrogel Loaded with Anthocyanins Shipin gongye ke-ji anthocyanins chitosan hydrogel stability ph response sustained release properties dynamics |
| title | Preparation and Properties of Chitosan Salicylaldehyde Hydrogel Loaded with Anthocyanins |
| title_full | Preparation and Properties of Chitosan Salicylaldehyde Hydrogel Loaded with Anthocyanins |
| title_fullStr | Preparation and Properties of Chitosan Salicylaldehyde Hydrogel Loaded with Anthocyanins |
| title_full_unstemmed | Preparation and Properties of Chitosan Salicylaldehyde Hydrogel Loaded with Anthocyanins |
| title_short | Preparation and Properties of Chitosan Salicylaldehyde Hydrogel Loaded with Anthocyanins |
| title_sort | preparation and properties of chitosan salicylaldehyde hydrogel loaded with anthocyanins |
| topic | anthocyanins chitosan hydrogel stability ph response sustained release properties dynamics |
| url | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022060293 |
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