The Secretome of Human Bronchial Epithelial Cells Exposed to Fine Atmospheric Particles Induces Fibroblast Proliferation

The Secretome of Human Bronchial Epithelial Cells Exposed to Fine Atmospheric Particles Induces Fibroblast Proliferation

Chronic exposure to particulate pollution is suspected to exacerbate inflammatory respiratory diseases such as asthma characterized by an airway remodelling involving fibrosis. Our study aims to investigate whether the secretome from human bronchial epithelial (HBE) cells exposed to fine particulate...

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Bibliographic Details
Main Authors: Laurent Martinon, Laura Boublil, Armelle Baeza-Squiban
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Challenges
Subjects:
amphiregulin
TGFa
airway remodeling
fibrosis
PM
airway epithelium
EGFR ligands
Online Access:http://www.mdpi.com/2078-1547/4/2/188

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