Determining the Best Appropriate Level of Endometrial Thickness in the Outcome of Intra-Cytoplasmic Sperm Injection
BACKGROUND AND OBJECTIVE: The success rate of intra-cytoplasmic sperm injection (ICSI) is dependent not only on egg and sperm quality but also is related to endometrial receptivity. Today one of the main obstacles in the treatment of infertility is reduced implantation rates in infertility treatment...
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2012-07-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
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| Online Access: | http://jbums.org/article-1-4147-en.html |
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| author | Z Basirat, S Esmailzadeh GH.A Jorsaraei, M Firoozpour S Abdolhashempour |
| author_facet | Z Basirat, S Esmailzadeh GH.A Jorsaraei, M Firoozpour S Abdolhashempour |
| author_sort | Z Basirat, |
| collection | DOAJ |
| description | BACKGROUND AND OBJECTIVE: The success rate of intra-cytoplasmic sperm injection (ICSI) is dependent not only on egg and sperm quality but also is related to endometrial receptivity. Today one of the main obstacles in the treatment of infertility is reduced implantation rates in infertility treatment cycles, despite having some good quality embryos. Therefore, this study was designed to determine the best appropriate level of endometrial thickness on intra-cytoplasmic sperm injection outcome.METHODS: A cross-sectional study was performed on 198 patients in ICSI/ET cycles in Fatemeh-Zahra Infertility center of Babol University of medical science (Babol, Iran) during 2009-2010. Sonography feature of the endometrium (thickness and pattern) and various other variables (maternal age, cause and duration of infertility and number of retrieved oocyte) in pregnant (according to positive B-HCG test and presence of fetal heart beat on vaginal sonography) and non pregnant patients were compared.FINDINGS: A total of 198 cycles were analyzed. Pregnancy rate was 46 (23.2%). Most pregnancy rate (50%) was among patients with an endometrial thickness 9.2-11.7 mm. Duration, type and etiology of infertility, endometrial pattern and number of retrieved oocyte were not correlated to ICSI outcome. Endometrial thickness and maternal age is a predictive factor of success rate in ICSI treatment cycles (p<0.05). CONCLUSION: Endometrial thickness is a good predictive factor for ICSI outcome. We can decide for embryo transfer or freezing if endometrial thickness and pattern are inappropriate. |
| first_indexed | 2024-12-20T04:26:09Z |
| format | Article |
| id | doaj.art-ade564ad704c4f52ac301db19d17cf4b |
| institution | Directory Open Access Journal |
| issn | 1561-4107 2251-7170 |
| language | English |
| last_indexed | 2024-12-20T04:26:09Z |
| publishDate | 2012-07-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| spelling | doaj.art-ade564ad704c4f52ac301db19d17cf4b2022-12-21T19:53:31ZengBabol University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul1561-41072251-71702012-07-011441521Determining the Best Appropriate Level of Endometrial Thickness in the Outcome of Intra-Cytoplasmic Sperm InjectionZ Basirat,0S Esmailzadeh1GH.A Jorsaraei,2M Firoozpour3S Abdolhashempour4 BACKGROUND AND OBJECTIVE: The success rate of intra-cytoplasmic sperm injection (ICSI) is dependent not only on egg and sperm quality but also is related to endometrial receptivity. Today one of the main obstacles in the treatment of infertility is reduced implantation rates in infertility treatment cycles, despite having some good quality embryos. Therefore, this study was designed to determine the best appropriate level of endometrial thickness on intra-cytoplasmic sperm injection outcome.METHODS: A cross-sectional study was performed on 198 patients in ICSI/ET cycles in Fatemeh-Zahra Infertility center of Babol University of medical science (Babol, Iran) during 2009-2010. Sonography feature of the endometrium (thickness and pattern) and various other variables (maternal age, cause and duration of infertility and number of retrieved oocyte) in pregnant (according to positive B-HCG test and presence of fetal heart beat on vaginal sonography) and non pregnant patients were compared.FINDINGS: A total of 198 cycles were analyzed. Pregnancy rate was 46 (23.2%). Most pregnancy rate (50%) was among patients with an endometrial thickness 9.2-11.7 mm. Duration, type and etiology of infertility, endometrial pattern and number of retrieved oocyte were not correlated to ICSI outcome. Endometrial thickness and maternal age is a predictive factor of success rate in ICSI treatment cycles (p<0.05). CONCLUSION: Endometrial thickness is a good predictive factor for ICSI outcome. We can decide for embryo transfer or freezing if endometrial thickness and pattern are inappropriate.http://jbums.org/article-1-4147-en.htmlinfertilityendometrial thicknessendometrial patternintra-cytoplasmic sperm injection |
| spellingShingle | Z Basirat, S Esmailzadeh GH.A Jorsaraei, M Firoozpour S Abdolhashempour Determining the Best Appropriate Level of Endometrial Thickness in the Outcome of Intra-Cytoplasmic Sperm Injection Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul infertility endometrial thickness endometrial pattern intra-cytoplasmic sperm injection |
| title | Determining the Best Appropriate Level of Endometrial Thickness in the Outcome of Intra-Cytoplasmic Sperm Injection |
| title_full | Determining the Best Appropriate Level of Endometrial Thickness in the Outcome of Intra-Cytoplasmic Sperm Injection |
| title_fullStr | Determining the Best Appropriate Level of Endometrial Thickness in the Outcome of Intra-Cytoplasmic Sperm Injection |
| title_full_unstemmed | Determining the Best Appropriate Level of Endometrial Thickness in the Outcome of Intra-Cytoplasmic Sperm Injection |
| title_short | Determining the Best Appropriate Level of Endometrial Thickness in the Outcome of Intra-Cytoplasmic Sperm Injection |
| title_sort | determining the best appropriate level of endometrial thickness in the outcome of intra cytoplasmic sperm injection |
| topic | infertility endometrial thickness endometrial pattern intra-cytoplasmic sperm injection |
| url | http://jbums.org/article-1-4147-en.html |
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