Healing effects of Ziziphus jujuba hydroalcoholic extract with exercise training on histopathological changes of male wistar rats testicular tissue in response to Boldenone steroid administration
Background and objectives: Anabolic steroids are routinely consumed by athletes. Therefore, this study was conducted to investigate the effect of Boldenone (BOL) on testicular tissue and the healing effect of jujube (Ziziphus jujuba) hydroalcoholic extract in addition to physical exercise. Methods:...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Golestan University of Medical Sciences
2018-06-01
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| Series: | Jorjani Biomedicine Journal |
| Subjects: | |
| Online Access: | http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-24-114&slc_lang=en&sid=1 |
| _version_ | 1818569957216092160 |
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| author | Behrooz Yahyaei Mahnaz Nouri Hamid Matmir |
| author_facet | Behrooz Yahyaei Mahnaz Nouri Hamid Matmir |
| author_sort | Behrooz Yahyaei |
| collection | DOAJ |
| description | Background and objectives: Anabolic steroids are routinely consumed by athletes. Therefore, this study was conducted to investigate the effect of Boldenone (BOL) on testicular tissue and the healing effect of jujube (Ziziphus jujuba) hydroalcoholic extract in addition to physical exercise.
Methods: In the present case–control study, 42 male wistar rats were purchased and divided into 3 experimental groups. 28 rats were subjected to BOL injection and subsequently divided into 4 groups. The control group, Sham and 8-week BOL group which was also divided into 4 subsequent groups of controlling BOL complications after 8 weeks, untreated control, jujube extract and jujube extract along with physical exercise.
Results: In the present study we found that jujube extract exerted healing effects on all groups pf treated rats in addition to the exercise training groups.
Conclusion: Jujube extract along with physical exercise may exert healing effects on testicular tissue after administration of anabolic BOL steroid. |
| first_indexed | 2024-12-14T06:54:29Z |
| format | Article |
| id | doaj.art-ade6e8391ec045d19ea267e3c09da5bc |
| institution | Directory Open Access Journal |
| issn | 2645-3509 |
| language | English |
| last_indexed | 2024-12-14T06:54:29Z |
| publishDate | 2018-06-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | Jorjani Biomedicine Journal |
| spelling | doaj.art-ade6e8391ec045d19ea267e3c09da5bc2022-12-21T23:12:46ZengGolestan University of Medical SciencesJorjani Biomedicine Journal2645-35092018-06-01611221Healing effects of Ziziphus jujuba hydroalcoholic extract with exercise training on histopathological changes of male wistar rats testicular tissue in response to Boldenone steroid administrationBehrooz Yahyaei0Mahnaz Nouri1Hamid Matmir2 Department of Basic Science, Faculty of Medical Sciences, Shahrood Branch, Islamic Azad University, Shahrood, Iran Department of Obstetrics and Gynecology, Faculty of Medical Sciences, Shahrood Branch, Islamic Azad University, Shahrood, Iran Department of Obstetrics and Gynecology, Faculty of Medical Sciences, Shahrood Branch, Islamic Azad University, Shahrood, Iran Background and objectives: Anabolic steroids are routinely consumed by athletes. Therefore, this study was conducted to investigate the effect of Boldenone (BOL) on testicular tissue and the healing effect of jujube (Ziziphus jujuba) hydroalcoholic extract in addition to physical exercise. Methods: In the present case–control study, 42 male wistar rats were purchased and divided into 3 experimental groups. 28 rats were subjected to BOL injection and subsequently divided into 4 groups. The control group, Sham and 8-week BOL group which was also divided into 4 subsequent groups of controlling BOL complications after 8 weeks, untreated control, jujube extract and jujube extract along with physical exercise. Results: In the present study we found that jujube extract exerted healing effects on all groups pf treated rats in addition to the exercise training groups. Conclusion: Jujube extract along with physical exercise may exert healing effects on testicular tissue after administration of anabolic BOL steroid.http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-24-114&slc_lang=en&sid=1BoldenoneZiziphus jujubaHydroalcoholic extractTesticular tissueWistar rat |
| spellingShingle | Behrooz Yahyaei Mahnaz Nouri Hamid Matmir Healing effects of Ziziphus jujuba hydroalcoholic extract with exercise training on histopathological changes of male wistar rats testicular tissue in response to Boldenone steroid administration Jorjani Biomedicine Journal Boldenone Ziziphus jujuba Hydroalcoholic extract Testicular tissue Wistar rat |
| title | Healing effects of Ziziphus jujuba hydroalcoholic extract with exercise training on histopathological changes of male wistar rats testicular tissue in response to Boldenone steroid administration |
| title_full | Healing effects of Ziziphus jujuba hydroalcoholic extract with exercise training on histopathological changes of male wistar rats testicular tissue in response to Boldenone steroid administration |
| title_fullStr | Healing effects of Ziziphus jujuba hydroalcoholic extract with exercise training on histopathological changes of male wistar rats testicular tissue in response to Boldenone steroid administration |
| title_full_unstemmed | Healing effects of Ziziphus jujuba hydroalcoholic extract with exercise training on histopathological changes of male wistar rats testicular tissue in response to Boldenone steroid administration |
| title_short | Healing effects of Ziziphus jujuba hydroalcoholic extract with exercise training on histopathological changes of male wistar rats testicular tissue in response to Boldenone steroid administration |
| title_sort | healing effects of ziziphus jujuba hydroalcoholic extract with exercise training on histopathological changes of male wistar rats testicular tissue in response to boldenone steroid administration |
| topic | Boldenone Ziziphus jujuba Hydroalcoholic extract Testicular tissue Wistar rat |
| url | http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-24-114&slc_lang=en&sid=1 |
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