Progressive Facial Haemiatrophy (Parry–Romberg Syndrome) Treated with Hyaluronic Acid Fillers

Introduction: Parry–Romberg syndrome (PRS) is a rare neurocutaneous condition that can affect the skin, subcutaneous fat, muscle, and bone on one side of the face. PRS presents with progressive but self-limiting facial haemiatrophy, and its severity ranges from barely noticeable asymmetry to severe...

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Main Authors: Luciana Yacomotti, Daniel Alejandro Muszalski, Maria Cecilia Miksa, Sofía Duran, Natalia De Magistra, Victor Castilla
Format: Article
Language:English
Published: European Medical Journal 2023-07-01
Series:European Medical Journal Dermatology
Online Access:https://www.emjreviews.com/dermatology/article/progressive-facial-haemiatrophy-parry-romberg-syndrome-treated-with-hyaluronic-acid-fillers/
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author Luciana Yacomotti
Daniel Alejandro Muszalski
Maria Cecilia Miksa
Sofía Duran
Natalia De Magistra
Victor Castilla
author_facet Luciana Yacomotti
Daniel Alejandro Muszalski
Maria Cecilia Miksa
Sofía Duran
Natalia De Magistra
Victor Castilla
author_sort Luciana Yacomotti
collection DOAJ
description Introduction: Parry–Romberg syndrome (PRS) is a rare neurocutaneous condition that can affect the skin, subcutaneous fat, muscle, and bone on one side of the face. PRS presents with progressive but self-limiting facial haemiatrophy, and its severity ranges from barely noticeable asymmetry to severe disfigurement. The authors describe a 35-year-old male with right facial haemiatrophy. The patient presented in a stable condition at the initial consultation. Objectives: Adipose tissue autografts were the most used tool to treat many congenital or acquired facial deformities. The authors proposed using cross-linked hyaluronic acid (HA) fillers over those traditionally used to correct facial deformities due to PRS. Discussion: PRS is usually self-limiting, with the maximal progression of the disease 2–5 years after onset. There is no specific cure for PRS at present. After 7 years of progression from the onset, this patient entered a stable phase. Reconstructive treatment was then indicated, since there were no further signs of atrophy. Since adipose tissue autografts require complicated surgical skills, which take a lot of time and cost, the authors report a case of PRS augmented by HA filler in a 35-year-old male patient to suggest that HA filler could be a safe and simple alternative to surgical treatment. The authors conclude that HA fillers are a safe tool for treating facial deformities in patients with PRS.
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spelling doaj.art-adeb13878a3f4c74ad7039713a586c5c2023-12-12T16:56:35ZengEuropean Medical JournalEuropean Medical Journal Dermatology2054-62112023-07-0110.33590/emjdermatol/10303108Progressive Facial Haemiatrophy (Parry–Romberg Syndrome) Treated with Hyaluronic Acid FillersLuciana Yacomotti0Daniel Alejandro Muszalski1Maria Cecilia Miksa2Sofía Duran3Natalia De Magistra4Victor Castilla5Department of Family Medicine, Aesthetic Medicine, Los Angeles, California, USADepartment of Dermatology, Dermabaires, Ciudad Autónoma de Buenos Aires (CABA), ArgentinaDepartment of Plastic Surgery, Hospital Luis Güemes de Haedo, Centro Banegas Estética Médica, Buenos Aires, ArgentinaDepartment of Dermatology, Ciudad Autónoma de Buenos Aires (CABA), ArgentinaDepartment of Plastic Surgery, Ciudad Autónoma de Buenos Aires (CABA), ArgentinaDepartment of Family Medicine, Optum, Arcadia, California, USA Introduction: Parry–Romberg syndrome (PRS) is a rare neurocutaneous condition that can affect the skin, subcutaneous fat, muscle, and bone on one side of the face. PRS presents with progressive but self-limiting facial haemiatrophy, and its severity ranges from barely noticeable asymmetry to severe disfigurement. The authors describe a 35-year-old male with right facial haemiatrophy. The patient presented in a stable condition at the initial consultation. Objectives: Adipose tissue autografts were the most used tool to treat many congenital or acquired facial deformities. The authors proposed using cross-linked hyaluronic acid (HA) fillers over those traditionally used to correct facial deformities due to PRS. Discussion: PRS is usually self-limiting, with the maximal progression of the disease 2–5 years after onset. There is no specific cure for PRS at present. After 7 years of progression from the onset, this patient entered a stable phase. Reconstructive treatment was then indicated, since there were no further signs of atrophy. Since adipose tissue autografts require complicated surgical skills, which take a lot of time and cost, the authors report a case of PRS augmented by HA filler in a 35-year-old male patient to suggest that HA filler could be a safe and simple alternative to surgical treatment. The authors conclude that HA fillers are a safe tool for treating facial deformities in patients with PRS.https://www.emjreviews.com/dermatology/article/progressive-facial-haemiatrophy-parry-romberg-syndrome-treated-with-hyaluronic-acid-fillers/
spellingShingle Luciana Yacomotti
Daniel Alejandro Muszalski
Maria Cecilia Miksa
Sofía Duran
Natalia De Magistra
Victor Castilla
Progressive Facial Haemiatrophy (Parry–Romberg Syndrome) Treated with Hyaluronic Acid Fillers
European Medical Journal Dermatology
title Progressive Facial Haemiatrophy (Parry–Romberg Syndrome) Treated with Hyaluronic Acid Fillers
title_full Progressive Facial Haemiatrophy (Parry–Romberg Syndrome) Treated with Hyaluronic Acid Fillers
title_fullStr Progressive Facial Haemiatrophy (Parry–Romberg Syndrome) Treated with Hyaluronic Acid Fillers
title_full_unstemmed Progressive Facial Haemiatrophy (Parry–Romberg Syndrome) Treated with Hyaluronic Acid Fillers
title_short Progressive Facial Haemiatrophy (Parry–Romberg Syndrome) Treated with Hyaluronic Acid Fillers
title_sort progressive facial haemiatrophy parry romberg syndrome treated with hyaluronic acid fillers
url https://www.emjreviews.com/dermatology/article/progressive-facial-haemiatrophy-parry-romberg-syndrome-treated-with-hyaluronic-acid-fillers/
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