Instructing cells with programmable peptide DNA hybrids
The extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell orga...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms15982 |
| _version_ | 1818990651709063168 |
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| author | Ronit Freeman Nicholas Stephanopoulos Zaida Álvarez Jacob A Lewis Shantanu Sur Chris M Serrano Job Boekhoven Sungsoo S. Lee Samuel I. Stupp |
| author_facet | Ronit Freeman Nicholas Stephanopoulos Zaida Álvarez Jacob A Lewis Shantanu Sur Chris M Serrano Job Boekhoven Sungsoo S. Lee Samuel I. Stupp |
| author_sort | Ronit Freeman |
| collection | DOAJ |
| description | The extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell organisation. |
| first_indexed | 2024-12-20T19:57:46Z |
| format | Article |
| id | doaj.art-adec0b74d8f044eba6a16b4902f1965a |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T19:57:46Z |
| publishDate | 2017-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-adec0b74d8f044eba6a16b4902f1965a2022-12-21T19:28:08ZengNature PortfolioNature Communications2041-17232017-07-018111110.1038/ncomms15982Instructing cells with programmable peptide DNA hybridsRonit Freeman0Nicholas Stephanopoulos1Zaida Álvarez2Jacob A Lewis3Shantanu Sur4Chris M Serrano5Job Boekhoven6Sungsoo S. Lee7Samuel I. Stupp8Simpson Querrey Institute for BioNanotechnology, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversityDepartment of Biomedical Engineering, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversityDepartment of Materials Science and Engineering, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversityThe extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell organisation.https://doi.org/10.1038/ncomms15982 |
| spellingShingle | Ronit Freeman Nicholas Stephanopoulos Zaida Álvarez Jacob A Lewis Shantanu Sur Chris M Serrano Job Boekhoven Sungsoo S. Lee Samuel I. Stupp Instructing cells with programmable peptide DNA hybrids Nature Communications |
| title | Instructing cells with programmable peptide DNA hybrids |
| title_full | Instructing cells with programmable peptide DNA hybrids |
| title_fullStr | Instructing cells with programmable peptide DNA hybrids |
| title_full_unstemmed | Instructing cells with programmable peptide DNA hybrids |
| title_short | Instructing cells with programmable peptide DNA hybrids |
| title_sort | instructing cells with programmable peptide dna hybrids |
| url | https://doi.org/10.1038/ncomms15982 |
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