Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insight
AIM: To assess the association between buried optic disc drusen (BODD) location using spectral-domain optical coherence tomography (SD-OCT) and the location of associated visual field defects (VFD) using the Garway-Heath mapping. METHODS: This monocentric retrospective cross-sectional study was led...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2022-10-01
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| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/en_publish/2022/10/20221012.pdf |
| _version_ | 1828143373993639936 |
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| author | Brenda Nana Wandji Artémise Dugauquier Adèle Ehongo |
| author_facet | Brenda Nana Wandji Artémise Dugauquier Adèle Ehongo |
| author_sort | Brenda Nana Wandji |
| collection | DOAJ |
| description | AIM: To assess the association between buried optic disc drusen (BODD) location using spectral-domain optical coherence tomography (SD-OCT) and the location of associated visual field defects (VFD) using the Garway-Heath mapping. METHODS: This monocentric retrospective cross-sectional study was led at the authors' institution. Adult patients diagnosed with BODD who had complete records with a reliable Humphrey® 24-2 visual field, macular, and papillary OCT were enrolled. Fisher's exact test was used to measure the association between BODD location and VFD distribution according to Garway-Heath's mapping. RESULTS: Totally 20 eyes of 15 patients were included (60% females). The median age (interquartile range) was 63 (43)y and the median best corrected visual acuity (BCVA) was -0.08 (0.08) log MAR. BODD were mostly located in zones A, E, and F. The minimal rim width (MRW) was globally preserved. The retinal nerve fiber layer (RNFL) was predominantly altered in zones D, E, and F. There was a significant correlation between BODD location and that of RNFL alterations in zones D (P=0.03) and E (P=0.025); Moreover, the presence of BODD in the E zone was significantly related to damaged RNFL in the neighbouring sectors D and F (P=0.012; P=0.02 respectively). Sixty-three percent (12/19) of visual fields were abnormal and there was a significant match (Phi=0.7, P=0.009) between drusen location and VFD only in zone D. CONCLUSION: BODD do not only affect young patients and can be more harmful than usually expected, as we found VFD in 63% of cases. There is a correspondence between BODD location, RNFL damage, and VFD distributions. The presence of BODD induces the overestimation of MRW, thereby disrupting its sensitivity as an early indicator of ganglion fibers damage. |
| first_indexed | 2024-04-11T19:56:12Z |
| format | Article |
| id | doaj.art-adefb011c5f545d8871349a8779e198d |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-04-11T19:56:12Z |
| publishDate | 2022-10-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-adefb011c5f545d8871349a8779e198d2022-12-22T04:06:00ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982022-10-0115101641164910.18240/ijo.2022.10.1220221012Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insightBrenda Nana Wandji0Artémise Dugauquier1Adèle Ehongo2Brenda Nana Wandji. Faculty of Medicine, Université Libre de Bruxelles, Brussels 1070, Belgium. Brenda.Nana.Wandji@ulb.beDepartment of Ophthalmology, Erasme Hospital, Brussels 1070, BelgiumDepartment of Ophthalmology, Erasme Hospital, Brussels 1070, BelgiumAIM: To assess the association between buried optic disc drusen (BODD) location using spectral-domain optical coherence tomography (SD-OCT) and the location of associated visual field defects (VFD) using the Garway-Heath mapping. METHODS: This monocentric retrospective cross-sectional study was led at the authors' institution. Adult patients diagnosed with BODD who had complete records with a reliable Humphrey® 24-2 visual field, macular, and papillary OCT were enrolled. Fisher's exact test was used to measure the association between BODD location and VFD distribution according to Garway-Heath's mapping. RESULTS: Totally 20 eyes of 15 patients were included (60% females). The median age (interquartile range) was 63 (43)y and the median best corrected visual acuity (BCVA) was -0.08 (0.08) log MAR. BODD were mostly located in zones A, E, and F. The minimal rim width (MRW) was globally preserved. The retinal nerve fiber layer (RNFL) was predominantly altered in zones D, E, and F. There was a significant correlation between BODD location and that of RNFL alterations in zones D (P=0.03) and E (P=0.025); Moreover, the presence of BODD in the E zone was significantly related to damaged RNFL in the neighbouring sectors D and F (P=0.012; P=0.02 respectively). Sixty-three percent (12/19) of visual fields were abnormal and there was a significant match (Phi=0.7, P=0.009) between drusen location and VFD only in zone D. CONCLUSION: BODD do not only affect young patients and can be more harmful than usually expected, as we found VFD in 63% of cases. There is a correspondence between BODD location, RNFL damage, and VFD distributions. The presence of BODD induces the overestimation of MRW, thereby disrupting its sensitivity as an early indicator of ganglion fibers damage.http://ies.ijo.cn/en_publish/2022/10/20221012.pdfburied optic disc drusenvisual fieldspectral-domain optical coherence tomographygarway-heath mappingretinal nerve fiber layer |
| spellingShingle | Brenda Nana Wandji Artémise Dugauquier Adèle Ehongo Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insight International Journal of Ophthalmology buried optic disc drusen visual field spectral-domain optical coherence tomography garway-heath mapping retinal nerve fiber layer |
| title | Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insight |
| title_full | Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insight |
| title_fullStr | Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insight |
| title_full_unstemmed | Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insight |
| title_short | Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insight |
| title_sort | visual field defects and retinal nerve fiber layer damage in buried optic disc drusen a new insight |
| topic | buried optic disc drusen visual field spectral-domain optical coherence tomography garway-heath mapping retinal nerve fiber layer |
| url | http://ies.ijo.cn/en_publish/2022/10/20221012.pdf |
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