Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study
ABSTRACT. Additional clinical tools should be investigated to facilitate and aid the early diagnosis of cognitive decline. Postural control worsens with aging and this may be related to pathological cognitive impairment. Objective: to compare the balance of older adults without dementia in a contro...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Associação Neurologia Cognitiva e do Comportamento
2019-06-01
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| Series: | Dementia & Neuropsychologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000200196&tlng=en |
| _version_ | 1818988838562824192 |
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| author | Paula Sant’Anna Felipe de Oliveira Silva Ana Carolina de Mello Alves Rodrigues Jéssica Plácido José Vinicius Ferreira Estele Caroline Welter Meereis Jomilto Praxedes Valeska Marinho Jerson Laks Renato Sobral Monteiro-Junior Andrea Camaz Deslandes |
| author_facet | Paula Sant’Anna Felipe de Oliveira Silva Ana Carolina de Mello Alves Rodrigues Jéssica Plácido José Vinicius Ferreira Estele Caroline Welter Meereis Jomilto Praxedes Valeska Marinho Jerson Laks Renato Sobral Monteiro-Junior Andrea Camaz Deslandes |
| author_sort | Paula Sant’Anna |
| collection | DOAJ |
| description | ABSTRACT. Additional clinical tools should be investigated to facilitate and aid the early diagnosis of cognitive decline. Postural control worsens with aging and this may be related to pathological cognitive impairment. Objective: to compare the balance of older adults without dementia in a control group (CG) and with Alzheimer’s disease (AD), to observe the possible association with the independent variables (diagnosis, age, gender, and global cognition) and to verify the best posturographic analyses to determine the difference between the groups. Methods: 86 older adults (AD = 48; CG = 38) were evaluated using the Berg Balance Scale (BBS) and postural control was assessed by stabilometry on the Wii Balance Board ® (WBB). Independent T, Mann-Whitney U-tests, Effect Size (ES) and a linear regression were performed. Results: there was a significant difference for Elliptical Area, Total Velocity, Medio-Lateral displacements with closed eyes and open eyes, antero-posterior, with closed eyes and BBS between groups. These variables showed a large effect size for BBS (-1.02), Elliptical Area (0.83) with closed eyes, Medio-Lateral (0.80, 0.96) and Total Velocity (0.92; 1.10) with eyes open and eyes closed, respectively. Regression indicated global cognition accompanied by age, gender, and diagnosis influenced postural control. Conclusion: patients with AD showed impaired postural control compared to Control Group subjects. Total Velocity with closed eyes was the most sensitive parameter for differentiating groups and should be better investigated as a possible motor biomarker of dementia in posturographic analysis with WBB. |
| first_indexed | 2024-12-20T19:28:57Z |
| format | Article |
| id | doaj.art-adf0b98a8400438a843170ec3eb870c1 |
| institution | Directory Open Access Journal |
| issn | 1980-5764 |
| language | English |
| last_indexed | 2024-12-20T19:28:57Z |
| publishDate | 2019-06-01 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| record_format | Article |
| series | Dementia & Neuropsychologia |
| spelling | doaj.art-adf0b98a8400438a843170ec3eb870c12022-12-21T19:28:50ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-57642019-06-0113219620210.1590/1980-57642018dn13-020008Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional studyPaula Sant’AnnaFelipe de Oliveira SilvaAna Carolina de Mello Alves RodriguesJéssica PlácidoJosé Vinicius FerreiraEstele Caroline Welter MeereisJomilto PraxedesValeska MarinhoJerson LaksRenato Sobral Monteiro-JuniorAndrea Camaz DeslandesABSTRACT. Additional clinical tools should be investigated to facilitate and aid the early diagnosis of cognitive decline. Postural control worsens with aging and this may be related to pathological cognitive impairment. Objective: to compare the balance of older adults without dementia in a control group (CG) and with Alzheimer’s disease (AD), to observe the possible association with the independent variables (diagnosis, age, gender, and global cognition) and to verify the best posturographic analyses to determine the difference between the groups. Methods: 86 older adults (AD = 48; CG = 38) were evaluated using the Berg Balance Scale (BBS) and postural control was assessed by stabilometry on the Wii Balance Board ® (WBB). Independent T, Mann-Whitney U-tests, Effect Size (ES) and a linear regression were performed. Results: there was a significant difference for Elliptical Area, Total Velocity, Medio-Lateral displacements with closed eyes and open eyes, antero-posterior, with closed eyes and BBS between groups. These variables showed a large effect size for BBS (-1.02), Elliptical Area (0.83) with closed eyes, Medio-Lateral (0.80, 0.96) and Total Velocity (0.92; 1.10) with eyes open and eyes closed, respectively. Regression indicated global cognition accompanied by age, gender, and diagnosis influenced postural control. Conclusion: patients with AD showed impaired postural control compared to Control Group subjects. Total Velocity with closed eyes was the most sensitive parameter for differentiating groups and should be better investigated as a possible motor biomarker of dementia in posturographic analysis with WBB.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000200196&tlng=enmotor biomarkerAlzheimer’s diseasepostural controlbalancedementiaolder adults |
| spellingShingle | Paula Sant’Anna Felipe de Oliveira Silva Ana Carolina de Mello Alves Rodrigues Jéssica Plácido José Vinicius Ferreira Estele Caroline Welter Meereis Jomilto Praxedes Valeska Marinho Jerson Laks Renato Sobral Monteiro-Junior Andrea Camaz Deslandes Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study Dementia & Neuropsychologia motor biomarker Alzheimer’s disease postural control balance dementia older adults |
| title | Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
| title_full | Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
| title_fullStr | Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
| title_full_unstemmed | Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
| title_short | Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
| title_sort | posturographic analysis of older adults without dementia and patients with alzheimer s disease a cross sectional study |
| topic | motor biomarker Alzheimer’s disease postural control balance dementia older adults |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000200196&tlng=en |
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