Molecular imaging of pulmonary diseases

Abstract Imaging holds an important role in the diagnosis of lung diseases. Along with clinical tests, noninvasive imaging techniques provide complementary and valuable information that enables a complete differential diagnosis. Various novel molecular imaging tools are currently under investigation...

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Main Authors: Julien Dimastromatteo, Eric J. Charles, Victor E. Laubach
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-018-0716-0
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author Julien Dimastromatteo
Eric J. Charles
Victor E. Laubach
author_facet Julien Dimastromatteo
Eric J. Charles
Victor E. Laubach
author_sort Julien Dimastromatteo
collection DOAJ
description Abstract Imaging holds an important role in the diagnosis of lung diseases. Along with clinical tests, noninvasive imaging techniques provide complementary and valuable information that enables a complete differential diagnosis. Various novel molecular imaging tools are currently under investigation aimed toward achieving a better understanding of lung disease physiopathology as well as early detection and accurate diagnosis leading to targeted treatment. Recent research on molecular imaging methods that may permit differentiation of the cellular and molecular components of pulmonary disease and monitoring of immune activation are detailed in this review. The application of molecular imaging to lung disease is currently in its early stage, especially compared to other organs or tissues, but future studies will undoubtedly reveal useful pulmonary imaging probes and imaging modalities.
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spelling doaj.art-adf3aea10c234edcb5e6c640ea3b0f602022-12-21T23:56:39ZengBMCRespiratory Research1465-993X2018-01-0119111110.1186/s12931-018-0716-0Molecular imaging of pulmonary diseasesJulien Dimastromatteo0Eric J. Charles1Victor E. Laubach2Department of Biomedical Engineering, University of VirginiaDepartment of Surgery, University of VirginiaDepartment of Surgery, University of VirginiaAbstract Imaging holds an important role in the diagnosis of lung diseases. Along with clinical tests, noninvasive imaging techniques provide complementary and valuable information that enables a complete differential diagnosis. Various novel molecular imaging tools are currently under investigation aimed toward achieving a better understanding of lung disease physiopathology as well as early detection and accurate diagnosis leading to targeted treatment. Recent research on molecular imaging methods that may permit differentiation of the cellular and molecular components of pulmonary disease and monitoring of immune activation are detailed in this review. The application of molecular imaging to lung disease is currently in its early stage, especially compared to other organs or tissues, but future studies will undoubtedly reveal useful pulmonary imaging probes and imaging modalities.http://link.springer.com/article/10.1186/s12931-018-0716-0Molecular imagingPulmonary diseaseSPECTPET
spellingShingle Julien Dimastromatteo
Eric J. Charles
Victor E. Laubach
Molecular imaging of pulmonary diseases
Respiratory Research
Molecular imaging
Pulmonary disease
SPECT
PET
title Molecular imaging of pulmonary diseases
title_full Molecular imaging of pulmonary diseases
title_fullStr Molecular imaging of pulmonary diseases
title_full_unstemmed Molecular imaging of pulmonary diseases
title_short Molecular imaging of pulmonary diseases
title_sort molecular imaging of pulmonary diseases
topic Molecular imaging
Pulmonary disease
SPECT
PET
url http://link.springer.com/article/10.1186/s12931-018-0716-0
work_keys_str_mv AT juliendimastromatteo molecularimagingofpulmonarydiseases
AT ericjcharles molecularimagingofpulmonarydiseases
AT victorelaubach molecularimagingofpulmonarydiseases