The Negative Effect of Mean Perfusion Pressure on the Development of Acute Kidney Injury after Transcatheter Aortic Valve Implantation

Abstract Objective: To evaluate the predictive value of mean perfusion pressure (mPP) in the development of acute kidney injury (AKIN) after transcatheter aortic valve implantation (TAVI). Methods: One hundred and forty seven consecutive patients with aortic stenosis (AS) were evaluated for this s...

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Main Authors: Ilker Gül, Levent Cerit, Bihter Senturk, Mustafa Zungur, Mustafa Beyazıt Alkan, Hatice Kemal, Zeynep Cerit, Belma Yaman, Songul Usalp, Hamza Duygu
Format: Article
Language:English
Published: Sociedade Brasileira de Cirurgia Cardiovascular
Series:Brazilian Journal of Cardiovascular Surgery
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382018000600559&lng=en&tlng=en
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author Ilker Gül
Levent Cerit
Bihter Senturk
Mustafa Zungur
Mustafa Beyazıt Alkan
Hatice Kemal
Zeynep Cerit
Belma Yaman
Songul Usalp
Hamza Duygu
author_facet Ilker Gül
Levent Cerit
Bihter Senturk
Mustafa Zungur
Mustafa Beyazıt Alkan
Hatice Kemal
Zeynep Cerit
Belma Yaman
Songul Usalp
Hamza Duygu
author_sort Ilker Gül
collection DOAJ
description Abstract Objective: To evaluate the predictive value of mean perfusion pressure (mPP) in the development of acute kidney injury (AKIN) after transcatheter aortic valve implantation (TAVI). Methods: One hundred and forty seven consecutive patients with aortic stenosis (AS) were evaluated for this study and 133 of them were included. Mean arterial pressure (mAP) and central venous pressure (CVP) were used to calculate mPP before TAVI procedure (mPP = mAP-CVP). The occurrence of AKIN was evaluated with AKIN classification according to the Valve Academic Research Consortium-2 recommendations. The patients were divided into two groups according to the receiver operating characteristic (ROC) analysis of their mPP levels (high-risk group and low-risk group). Results: The AKIN prevalence was 22.6% in this study population. Baseline serum creatinine level, glomerular filtration rate, amount of contrast medium, and the level of mPP were determined as predictive factors for the development of AKIN. Conclusion: The occurrence of AKIN is associated with increased morbidity and mortality rates in patients with TAVI. In addition to the amount of contrast medium and basal kidney functions, our study showed that lower mPP was strongly associated with development of AKIN after TAVI.
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spelling doaj.art-adf558efc978458b8e13c37224276ec52022-12-22T03:28:20ZengSociedade Brasileira de Cirurgia CardiovascularBrazilian Journal of Cardiovascular Surgery1678-974133655956610.21470/1678-9741-2018-0137S0102-76382018000600559The Negative Effect of Mean Perfusion Pressure on the Development of Acute Kidney Injury after Transcatheter Aortic Valve ImplantationIlker GülLevent CeritBihter SenturkMustafa ZungurMustafa Beyazıt AlkanHatice KemalZeynep CeritBelma YamanSongul UsalpHamza DuyguAbstract Objective: To evaluate the predictive value of mean perfusion pressure (mPP) in the development of acute kidney injury (AKIN) after transcatheter aortic valve implantation (TAVI). Methods: One hundred and forty seven consecutive patients with aortic stenosis (AS) were evaluated for this study and 133 of them were included. Mean arterial pressure (mAP) and central venous pressure (CVP) were used to calculate mPP before TAVI procedure (mPP = mAP-CVP). The occurrence of AKIN was evaluated with AKIN classification according to the Valve Academic Research Consortium-2 recommendations. The patients were divided into two groups according to the receiver operating characteristic (ROC) analysis of their mPP levels (high-risk group and low-risk group). Results: The AKIN prevalence was 22.6% in this study population. Baseline serum creatinine level, glomerular filtration rate, amount of contrast medium, and the level of mPP were determined as predictive factors for the development of AKIN. Conclusion: The occurrence of AKIN is associated with increased morbidity and mortality rates in patients with TAVI. In addition to the amount of contrast medium and basal kidney functions, our study showed that lower mPP was strongly associated with development of AKIN after TAVI.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382018000600559&lng=en&tlng=enTranscatheter Aortic Valve ReplacementKidneyAcute Kidney InjuryPerfusion
spellingShingle Ilker Gül
Levent Cerit
Bihter Senturk
Mustafa Zungur
Mustafa Beyazıt Alkan
Hatice Kemal
Zeynep Cerit
Belma Yaman
Songul Usalp
Hamza Duygu
The Negative Effect of Mean Perfusion Pressure on the Development of Acute Kidney Injury after Transcatheter Aortic Valve Implantation
Brazilian Journal of Cardiovascular Surgery
Transcatheter Aortic Valve Replacement
Kidney
Acute Kidney Injury
Perfusion
title The Negative Effect of Mean Perfusion Pressure on the Development of Acute Kidney Injury after Transcatheter Aortic Valve Implantation
title_full The Negative Effect of Mean Perfusion Pressure on the Development of Acute Kidney Injury after Transcatheter Aortic Valve Implantation
title_fullStr The Negative Effect of Mean Perfusion Pressure on the Development of Acute Kidney Injury after Transcatheter Aortic Valve Implantation
title_full_unstemmed The Negative Effect of Mean Perfusion Pressure on the Development of Acute Kidney Injury after Transcatheter Aortic Valve Implantation
title_short The Negative Effect of Mean Perfusion Pressure on the Development of Acute Kidney Injury after Transcatheter Aortic Valve Implantation
title_sort negative effect of mean perfusion pressure on the development of acute kidney injury after transcatheter aortic valve implantation
topic Transcatheter Aortic Valve Replacement
Kidney
Acute Kidney Injury
Perfusion
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382018000600559&lng=en&tlng=en
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