Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesia
Administration of local anesthesia is an integral procedure prior to dental treatments to minimize the associated pain. It is learned that its effect stays more than the time required for the dental procedure to be completed. This prolonged soft tissue anesthesia (STA) can be detrimental, inconvenie...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Journal of Indian Society of Pedodontics and Preventive Dentistry |
| Subjects: | |
| Online Access: | http://www.jisppd.com/article.asp?issn=0970-4388;year=2015;volume=33;issue=4;spage=265;epage=268;aulast=Grover |
| _version_ | 1811269400716640256 |
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| author | Harpreet Singh Grover Anil Gupta Neha Saksena Neha Saini |
| author_facet | Harpreet Singh Grover Anil Gupta Neha Saksena Neha Saini |
| author_sort | Harpreet Singh Grover |
| collection | DOAJ |
| description | Administration of local anesthesia is an integral procedure prior to dental treatments to minimize the associated pain. It is learned that its effect stays more than the time required for the dental procedure to be completed. This prolonged soft tissue anesthesia (STA) can be detrimental, inconvenient, and unnecessary. Phentolamine mesylate, a Food and Drug Administration-approved drug essentially serves the purpose of faster recovery from numbness at the site of local anesthesia. This article reviews the development of the drug phentolamine mesylate and its indication as a local anesthetic reversal agent. A literature search for phentolamine mesylate as a STA reversal agent was conducted in PubMed using the terms "dental local anesthesia reversal, phentolamine mesylate" up to March 2014. The search was limited to articles published in English. The search revealed 13 PubMed indexed articles stating the development and application of phentolamine mesylate. Phentolamine mesylate is an important step in the progress of developing patient care as well as an aid to the dental clinician. |
| first_indexed | 2024-04-12T21:41:21Z |
| format | Article |
| id | doaj.art-adf68d024ef34d62bea63c634b703813 |
| institution | Directory Open Access Journal |
| issn | 0970-4388 1998-3905 |
| language | English |
| last_indexed | 2024-04-12T21:41:21Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Society of Pedodontics and Preventive Dentistry |
| spelling | doaj.art-adf68d024ef34d62bea63c634b7038132022-12-22T03:15:45ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Pedodontics and Preventive Dentistry0970-43881998-39052015-01-0133426526810.4103/0970-4388.165646Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesiaHarpreet Singh GroverAnil GuptaNeha SaksenaNeha SainiAdministration of local anesthesia is an integral procedure prior to dental treatments to minimize the associated pain. It is learned that its effect stays more than the time required for the dental procedure to be completed. This prolonged soft tissue anesthesia (STA) can be detrimental, inconvenient, and unnecessary. Phentolamine mesylate, a Food and Drug Administration-approved drug essentially serves the purpose of faster recovery from numbness at the site of local anesthesia. This article reviews the development of the drug phentolamine mesylate and its indication as a local anesthetic reversal agent. A literature search for phentolamine mesylate as a STA reversal agent was conducted in PubMed using the terms "dental local anesthesia reversal, phentolamine mesylate" up to March 2014. The search was limited to articles published in English. The search revealed 13 PubMed indexed articles stating the development and application of phentolamine mesylate. Phentolamine mesylate is an important step in the progress of developing patient care as well as an aid to the dental clinician.http://www.jisppd.com/article.asp?issn=0970-4388;year=2015;volume=33;issue=4;spage=265;epage=268;aulast=GroverDental local anesthesialocal anesthesia reversalphentolamine mesylate |
| spellingShingle | Harpreet Singh Grover Anil Gupta Neha Saksena Neha Saini Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesia Journal of Indian Society of Pedodontics and Preventive Dentistry Dental local anesthesia local anesthesia reversal phentolamine mesylate |
| title | Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesia |
| title_full | Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesia |
| title_fullStr | Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesia |
| title_full_unstemmed | Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesia |
| title_short | Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesia |
| title_sort | phentolamine mesylate it s role as a reversal agent for unwarranted prolonged local analgesia |
| topic | Dental local anesthesia local anesthesia reversal phentolamine mesylate |
| url | http://www.jisppd.com/article.asp?issn=0970-4388;year=2015;volume=33;issue=4;spage=265;epage=268;aulast=Grover |
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