Evaluation of Salivary Flow Rate, pH and Buffer in Pre, Post & Post Menopausal Women on HRT
Background: Climateric is considered to be a natural phase of life which by definition is the period of life starting from decline in ovarian activity until after the end of ovarian function . It is accompanied by various health consequences that include the changes in saliva too. This study was...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2014-02-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/4067/78-%208158_F(H)_PF1(PAK)_PFA(AK).pdf |
| Summary: | Background: Climateric is considered to be a natural phase of
life which by definition is the period of life starting from decline
in ovarian activity until after the end of ovarian function . It is
accompanied by various health consequences that include the
changes in saliva too. This study was carried out to evaluate the
salivary flow rate, pH, buffering capacity in pre-menopausal,
post-menopausal and post-menopausal women on HRT.
Aims and objectives: (1) To evaluate the salivary flow rate, pH
of resting saliva and stimulated saliva and buffer capacity of
stimulated saliva in pre-menopausal, post-menopausal and
post-menopausal women on Hormone Replacement Therapy
(HRT). (2) To compare the above salivary findings between premenopausal, post-menopausal and post-menopausal women
on HRT.
Materials and Methods: The study was carried out on 60
patients. These patients were divided into three groups of 20
patients: Group 1: Pre-menopausal women (control), Group 2:
post-menopausal women (case), Group 3: post-menopausal
women on HRT (case).
The control group consisted of 20 women volunteers, having
regular ovulatory menstrual cycles with no known systemic
illness and deleterious habits and Group 2 consists of 20
post-menopausal women and Group 3 will consist of 20 postmenopausal women on HRT.
After clearing the mouth by swallowing, stimulated saliva
was collected after chewing paraffin for 10 mins in to a glass
centrifuge tube graded in 0.1 mL increments up to 10mL.in rare
cases the collection time will be reduced or extended (5-15 min),
salivary flow rate will be determined as ml/min, immediately
after collection, pH was determined by dipping pH test paper
directly into the sample of oral fluid, salivary buffer capacity was
determined by using saliva check buffer kit (GC corporation).
The data obtained was statistically evaluated using chi-square
test, fisher exact test ANOVA analysis.
Results: In our study we found salivary flow rate significantly
lower in the post-menopausal women in comparison with the
menstruating women and also there was improvement in the
flow rate in individuals who were on HRT, it was also observed
that salivary pH of the post-menopausal group was significantly
lower than that of the control group, statistically significant
difference in buffer capacity values was found between the
groups however buffer capacity values were higher in the postmenopausal group than the control group.
Conclusion: From the above study it is clear that postmenopausal women will present with oral discomfort, while HRT
can improve the same. Hence our role as physicians and health
care providers is to incorporate preventive dental health care
in post-menopausal women and clearly inform patients about
both the benefits and the limitations of HRT. |
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| ISSN: | 2249-782X 0973-709X |