Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy.

Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy.

Polymorphic variants of the FTO (fat mass and obesity) gene associate with body mass index in humans, but the underlying molecular mechanisms have not been firmly determined. FTO is linked to energy homeostasis via amino acid sensing and is thought to activate the mammalian target of rapamycin compl...

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Bibliographic Details
Main Authors: Aleksander Aas, Pauline Isakson, Christian Bindesbøll, Endalkachew A Alemu, Arne Klungland, Anne Simonsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5347998?pdf=render

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