Critical physicochemical attributes of chitosan nanoparticles admixed lactose-PEG 3000 microparticles in pulmonary inhalation

Critical physicochemical attributes of chitosan nanoparticles admixed lactose-PEG 3000 microparticles in pulmonary inhalation

Chitosan nanoparticles are exhalation prone and agglomerative to pulmonary inhalation. Blending nanoparticles with lactose microparticles (∼5 µm) could mutually reduce their agglomeration through surface adsorption phenomenon. The chitosan nanoparticles of varying size, size distribution, zeta poten...

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Bibliographic Details
Main Authors: Nasser Alhajj, Zabliza Zakaria, Idanawati Naharudin, Fakhrul Ahsan, Wenji Li, Tin Wui Wong
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Chitosan
Inhalation
Nanoparticle
Pulmonary
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087618313187

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