Expression Profile of Human Renal Mesangial Cells Is Altered by Infection with Pathogenic Puumala Orthohantavirus

Expression Profile of Human Renal Mesangial Cells Is Altered by Infection with Pathogenic Puumala Orthohantavirus

Acute kidney injury (AKI) with proteinuria is a hallmark of infections with Eurasian orthohantaviruses. Different kidney cells are identified as target cells of hantaviruses. Mesangial cells may play a central role in the pathogenesis of AKI by regulation of inflammatory mediators and signaling casc...

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Bibliographic Details
Main Authors: Christian Nusshag, Lukas Boegelein, Pamela Schreiber, Sandra Essbauer, Anja Osberghaus, Martin Zeier, Ellen Krautkrämer
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Viruses
Subjects:
orthohantavirus
mesangial cell
kidney
glomerulus
proteome
acute kidney injury
Online Access:https://www.mdpi.com/1999-4915/14/4/823

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