The Effect of Peripheral Immune Cell Counts on the Risk of Multiple Sclerosis: A Mendelian Randomization Study

The Effect of Peripheral Immune Cell Counts on the Risk of Multiple Sclerosis: A Mendelian Randomization Study

ObjectivesMultiple sclerosis (MS) is a complex central nervous system (CNS) demyelinating disease, the etiology of which involves the interplay between genetic and environmental factors. We aimed to determine whether genetically predicted peripheral immune cell counts may have a causal effect on MS....

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Bibliographic Details
Main Authors: Di He, Liyang Liu, Dongchao Shen, Peng Zou, Liying Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
mendelian randomization (MR)
genome wide association study (GWAS)
peripheral immune cell count
NKT cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.867693/full

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