Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review
Abstract Background Medicinal plants have been used traditionally since centuries for wound care and treatment of skin diseases both in human and animals. Skin diseases are one of the most common reasons for owners to take their dog to the veterinarian. The demands for treatment and prophylaxis of t...
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| Format: | Article |
| Language: | English |
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BMC
2019-05-01
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| Series: | BMC Veterinary Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12917-019-1854-4 |
| _version_ | 1818152502420307968 |
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| author | Milena Tresch Meike Mevissen Hannah Ayrle Matthias Melzig Petra Roosje Michael Walkenhorst |
| author_facet | Milena Tresch Meike Mevissen Hannah Ayrle Matthias Melzig Petra Roosje Michael Walkenhorst |
| author_sort | Milena Tresch |
| collection | DOAJ |
| description | Abstract Background Medicinal plants have been used traditionally since centuries for wound care and treatment of skin diseases both in human and animals. Skin diseases are one of the most common reasons for owners to take their dog to the veterinarian. The demands for treatment and prophylaxis of these diseases are broad. A wide range of bacteria including antibiotic-resistant bacteria can be involved, making the treatment challenging and bear an anthropo-zoonotic potential. The aim of this review is to systematically evaluate based on recent scientific literature, the potential of four medicinal plants to enrich the therapeutic options in pyoderma, canine atopic dermatitis, otitis externa, wounds and dermatophytosis in dogs. Results Based on four books and a survey among veterinarians specialized in phytotherapy, four medicinal plants were chosen as the subject of this systematic review: Calendula officinalis L. (Marigold), Hypericum perforatum L. agg. (St. John’s Wort), Matricaria chamomilla L. (syn. Matricaria recutita L., Chamomile) and Salvia officinalis L. (Sage). According to the PRISMA statement through literature research on two online databases a total of 8295 publications was screened and narrowed down to a final 138 publications for which full-text documents were analyzed for its content resulting in a total of 145 references (21 clinical, 24 in vivo and 100 in vitro references). Conclusions All four plants were proven to have antibacterial and antifungal effects of a rather broad spectrum including antibiotic-resistant bacteria. This makes them an interesting new option for the treatment of pyoderma, otitis externa, infected wounds and dermatophytosis. Marigold, St. John’s Wort and Chamomile showed wound-healing properties and are thus promising candidates in line to fill the therapeutic gap in canine wound-healing agents. St. John’s Wort and Chamomile also showed anti-inflammatory and other beneficial effects on healthy skin. Due to the wide range of beneficial effects of these medicinal plants, they should be taken into account for the treatment of dermatologic diseases in dogs at least in future clinical research. |
| first_indexed | 2024-12-11T13:55:44Z |
| format | Article |
| id | doaj.art-ae0a4c60b48b489d86ca837aff275dda |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-12-11T13:55:44Z |
| publishDate | 2019-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-ae0a4c60b48b489d86ca837aff275dda2022-12-22T01:04:05ZengBMCBMC Veterinary Research1746-61482019-05-0115111910.1186/s12917-019-1854-4Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic reviewMilena Tresch0Meike Mevissen1Hannah Ayrle2Matthias Melzig3Petra Roosje4Michael Walkenhorst5Division Veterinary Pharmacology & Toxicology, Department Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of BernDivision Veterinary Pharmacology & Toxicology, Department Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of BernDepartment of Livestock Sciences, Research Institute of Organic Agriculture (FiBL)Dahlem Centre of Plant Sciences, Institute of Pharmacy, Freie Universität BerlinDivision of Clinical Dermatology, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of BernDepartment of Livestock Sciences, Research Institute of Organic Agriculture (FiBL)Abstract Background Medicinal plants have been used traditionally since centuries for wound care and treatment of skin diseases both in human and animals. Skin diseases are one of the most common reasons for owners to take their dog to the veterinarian. The demands for treatment and prophylaxis of these diseases are broad. A wide range of bacteria including antibiotic-resistant bacteria can be involved, making the treatment challenging and bear an anthropo-zoonotic potential. The aim of this review is to systematically evaluate based on recent scientific literature, the potential of four medicinal plants to enrich the therapeutic options in pyoderma, canine atopic dermatitis, otitis externa, wounds and dermatophytosis in dogs. Results Based on four books and a survey among veterinarians specialized in phytotherapy, four medicinal plants were chosen as the subject of this systematic review: Calendula officinalis L. (Marigold), Hypericum perforatum L. agg. (St. John’s Wort), Matricaria chamomilla L. (syn. Matricaria recutita L., Chamomile) and Salvia officinalis L. (Sage). According to the PRISMA statement through literature research on two online databases a total of 8295 publications was screened and narrowed down to a final 138 publications for which full-text documents were analyzed for its content resulting in a total of 145 references (21 clinical, 24 in vivo and 100 in vitro references). Conclusions All four plants were proven to have antibacterial and antifungal effects of a rather broad spectrum including antibiotic-resistant bacteria. This makes them an interesting new option for the treatment of pyoderma, otitis externa, infected wounds and dermatophytosis. Marigold, St. John’s Wort and Chamomile showed wound-healing properties and are thus promising candidates in line to fill the therapeutic gap in canine wound-healing agents. St. John’s Wort and Chamomile also showed anti-inflammatory and other beneficial effects on healthy skin. Due to the wide range of beneficial effects of these medicinal plants, they should be taken into account for the treatment of dermatologic diseases in dogs at least in future clinical research.http://link.springer.com/article/10.1186/s12917-019-1854-4DogDermatologyCalendula officinalis L.Hypericum perforatum L.Matricaria chamomilla L.Salvia officinalis L. |
| spellingShingle | Milena Tresch Meike Mevissen Hannah Ayrle Matthias Melzig Petra Roosje Michael Walkenhorst Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review BMC Veterinary Research Dog Dermatology Calendula officinalis L. Hypericum perforatum L. Matricaria chamomilla L. Salvia officinalis L. |
| title | Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review |
| title_full | Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review |
| title_fullStr | Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review |
| title_full_unstemmed | Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review |
| title_short | Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review |
| title_sort | medicinal plants as therapeutic options for topical treatment in canine dermatology a systematic review |
| topic | Dog Dermatology Calendula officinalis L. Hypericum perforatum L. Matricaria chamomilla L. Salvia officinalis L. |
| url | http://link.springer.com/article/10.1186/s12917-019-1854-4 |
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