Extensive hearing loss induced by low‐frequency noise exposure
Abstract Background With little attention given to low‐frequency traffic noise and our understanding that cochlear function may be highly susceptible to low‐frequency noise, there is an urgent need to determine traffic noise‐induced hearing loss (NIHL), not only the hearing loss at low frequency but...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-04-01
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| Series: | Laryngoscope Investigative Otolaryngology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/lio2.752 |
| _version_ | 1818049991475724288 |
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| author | Junping Liu Jastin Antisdel Changming Liu Miaoan Chen Pin Dong Richard Fahlman Furong Ma Yongqiang Yu |
| author_facet | Junping Liu Jastin Antisdel Changming Liu Miaoan Chen Pin Dong Richard Fahlman Furong Ma Yongqiang Yu |
| author_sort | Junping Liu |
| collection | DOAJ |
| description | Abstract Background With little attention given to low‐frequency traffic noise and our understanding that cochlear function may be highly susceptible to low‐frequency noise, there is an urgent need to determine traffic noise‐induced hearing loss (NIHL), not only the hearing loss at low frequency but also the possible high‐frequency hearing loss. Methods The current study aims to investigate the potential for extensive hearing loss induced by exposure to 0.063 kHz octave band noise (OBN), which is an important component of low‐frequency traffic noise. The threshold of auditory brainstem response (ABR) was used to evaluate hearing function before and after noise exposure. Chinchillas were randomly assigned into seven different groups. Group 63‐3 h/6 h, Group 2 k‐3 h/6 h, and group 4 k‐3 h/6 h were exposed for either 3 or 6 h to 0.063, 2, and 4 kHz OBN at 90 dB SPL, respectively. The control group was not exposed to noise. Results Significant ABR threshold‐shifts (TS) were observed at 0.88, 2, 4, and 5.7 kHz in Group 63‐6 h, and at 2.8 and 4 kHz in Group 2 k‐6 h, and at 5.7 kHz in Group 4 k‐6 h. ABR‐TS were consistent with outer hair cell (OHC) losses, exposure to 0.063 kHz OBN at 90 dB SPL for 6 h induced large‐scale losses of OHC both in low‐ and high‐frequency region. Conclusions Exposure to 0.063 kHz low‐frequency OBN at 90 dB SPL for 6 h leads to significant hearing loss over an extensive range from low to high frequencies. |
| first_indexed | 2024-12-10T10:46:22Z |
| format | Article |
| id | doaj.art-ae0d7338593543fb9daea626202f56f3 |
| institution | Directory Open Access Journal |
| issn | 2378-8038 |
| language | English |
| last_indexed | 2024-12-10T10:46:22Z |
| publishDate | 2022-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Laryngoscope Investigative Otolaryngology |
| spelling | doaj.art-ae0d7338593543fb9daea626202f56f32022-12-22T01:52:08ZengWileyLaryngoscope Investigative Otolaryngology2378-80382022-04-017256457010.1002/lio2.752Extensive hearing loss induced by low‐frequency noise exposureJunping Liu0Jastin Antisdel1Changming Liu2Miaoan Chen3Pin Dong4Richard Fahlman5Furong Ma6Yongqiang Yu7Department of Otolaryngology – Head Neck Surgery, Mindong Hospital The Affiliated Mindong Hospital of Fujian Medical University Fuan ChinaDepartment of Otolaryngology – Head Neck Surgery Saint Louis University St. Louis Missouri USADepartment of Otolaryngology – Head Neck Surgery, Mindong Hospital The Affiliated Mindong Hospital of Fujian Medical University Fuan ChinaDepartment of Otolaryngology – Head Neck Surgery, Mindong Hospital The Affiliated Mindong Hospital of Fujian Medical University Fuan ChinaDepartment of Otolaryngology – Head Neck Surgery The First Hospital of Shanghai Jiaotong University Shanghai ChinaFaculty of Medicine University of Alberta Edmonton Alberta CanadaDepartment of Otolaryngology – Head Neck Surgery The Third Hospital of Peking University Beijing ChinaDepartment of Otolaryngology – Head Neck Surgery, Mindong Hospital The Affiliated Mindong Hospital of Fujian Medical University Fuan ChinaAbstract Background With little attention given to low‐frequency traffic noise and our understanding that cochlear function may be highly susceptible to low‐frequency noise, there is an urgent need to determine traffic noise‐induced hearing loss (NIHL), not only the hearing loss at low frequency but also the possible high‐frequency hearing loss. Methods The current study aims to investigate the potential for extensive hearing loss induced by exposure to 0.063 kHz octave band noise (OBN), which is an important component of low‐frequency traffic noise. The threshold of auditory brainstem response (ABR) was used to evaluate hearing function before and after noise exposure. Chinchillas were randomly assigned into seven different groups. Group 63‐3 h/6 h, Group 2 k‐3 h/6 h, and group 4 k‐3 h/6 h were exposed for either 3 or 6 h to 0.063, 2, and 4 kHz OBN at 90 dB SPL, respectively. The control group was not exposed to noise. Results Significant ABR threshold‐shifts (TS) were observed at 0.88, 2, 4, and 5.7 kHz in Group 63‐6 h, and at 2.8 and 4 kHz in Group 2 k‐6 h, and at 5.7 kHz in Group 4 k‐6 h. ABR‐TS were consistent with outer hair cell (OHC) losses, exposure to 0.063 kHz OBN at 90 dB SPL for 6 h induced large‐scale losses of OHC both in low‐ and high‐frequency region. Conclusions Exposure to 0.063 kHz low‐frequency OBN at 90 dB SPL for 6 h leads to significant hearing loss over an extensive range from low to high frequencies.https://doi.org/10.1002/lio2.752auditory brainstem responseextensive hearing losslow‐frequency noise |
| spellingShingle | Junping Liu Jastin Antisdel Changming Liu Miaoan Chen Pin Dong Richard Fahlman Furong Ma Yongqiang Yu Extensive hearing loss induced by low‐frequency noise exposure Laryngoscope Investigative Otolaryngology auditory brainstem response extensive hearing loss low‐frequency noise |
| title | Extensive hearing loss induced by low‐frequency noise exposure |
| title_full | Extensive hearing loss induced by low‐frequency noise exposure |
| title_fullStr | Extensive hearing loss induced by low‐frequency noise exposure |
| title_full_unstemmed | Extensive hearing loss induced by low‐frequency noise exposure |
| title_short | Extensive hearing loss induced by low‐frequency noise exposure |
| title_sort | extensive hearing loss induced by low frequency noise exposure |
| topic | auditory brainstem response extensive hearing loss low‐frequency noise |
| url | https://doi.org/10.1002/lio2.752 |
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