Metrological Characteristics of the Potentiometric Assay Developed for Determining the Antioxidant Activity of Ascorbic Acid
The potentiometric assay for determining the antioxidant activity of ascorbic acid has been developed and validated according to the following parameters: specificity, linearity, accuracy, repeatability, intermediate precision. The linearity was in the concentration range of 0.002 – 0.02 mol L–1 (r2...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy (Kharkiv, Ukraine)
2023-10-01
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| Series: | Журнал органічної та фармацевтичної хімії |
| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/276394 |
| Summary: | The potentiometric assay for determining the antioxidant activity of ascorbic acid has been developed and validated according to the following parameters: specificity, linearity, accuracy, repeatability, intermediate precision. The linearity was in the concentration range of 0.002 – 0.02 mol L–1 (r2 = 0.9993). The percentage of recovery was found to be in the range from 95.38 to 105.00 %. The values of %RSD for repeatability and intermediate precision were 1.86 and 1.95 %, respectively. The method is accurate and reliable, with the relative standard deviation of less than 2 %. It has been proven that the method developed is express, rapid, highly sensitive, accurate and sufficiently reliable. |
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| ISSN: | 2308-8303 2518-1548 |