Infection with COVID-19 promotes the progression of pancreatic cancer through the PI3K-AKT signaling pathway

Infection with COVID-19 promotes the progression of pancreatic cancer through the PI3K-AKT signaling pathway

Abstract Objective To investigate the effect of COVID-19 infection on pancreatic cancer. Methods Based on the mRNA-Seq data of COVID-19 patients and pancreatic cancer (PC) patients in the GEO database, we used a support vector machine (SVM), LASSO-Cox regression analysis and random forest tree (RF)...

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Bibliographic Details
Main Authors: Xusheng Zhang, Bendong Chen, Kejun Liu, Yongxin Ma, Yimin Liu, Hongcai Zhou, Peng Wei
Format: Article
Language:English
Published: Springer 2023-12-01
Series:Discover Oncology
Subjects:
COVID-19
Pancreatic cancer
Machine learning
PI3K-AKT signaling pathway
Support vector machine
Random forest tree
Online Access:https://doi.org/10.1007/s12672-023-00842-9

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