Impaired Pain Processing at a Brainstem Level Is Involved in Maladaptive Neuroplasticity in Patients with Chronic Complex Regional Pain Syndrome

Impaired Pain Processing at a Brainstem Level Is Involved in Maladaptive Neuroplasticity in Patients with Chronic Complex Regional Pain Syndrome

Neuroinflammatory mechanisms and maladaptive neuroplasticity underlie the progression of complex regional pain syndrome (CRPS), which is prototypical of central neuropathic pain conditions. While cortical maladaptive alterations are well described, little is known about the contribution of the brain...

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Bibliographic Details
Main Authors: Pauline Thoma, Nina Drämel, Matthias Grothe, Martin Lotze, Robert Fleischmann, Sebastian Strauss
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
complex regional pain syndrome
CRPS
central sensitization
brainstem
blink reflex
Online Access:https://www.mdpi.com/1422-0067/23/23/15368

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