Epidemiologic Investigation of Acute Q Fever in North of Iran
Background and purpose: Q fever is a worldwide zoonosis which is an endemic in many regions. Its diagnosis is usually missed especially in human. This research aimed at investigating acute Q fever among suspected patients in northern Iran. Materials and methods: This cross-sectional study was conduc...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2019-06-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-11863-en.html |
| _version_ | 1797943875708387328 |
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| author | Roya Ghasemian Ehsan Mostafavi Saber Esmaeili Sara Arabsheybani Lotfollah Davoodi |
| author_facet | Roya Ghasemian Ehsan Mostafavi Saber Esmaeili Sara Arabsheybani Lotfollah Davoodi |
| author_sort | Roya Ghasemian |
| collection | DOAJ |
| description | Background and purpose: Q fever is a worldwide zoonosis which is an endemic in many regions. Its diagnosis is usually missed especially in human. This research aimed at investigating acute Q fever among suspected patients in northern Iran.
Materials and methods: This cross-sectional study was conducted in 56 suspected cases of Q fever selected from 476 febrile patients admitted in Qaemshahr Razi Hospital, Iran 2016, with systemic or respiratory symptoms. Blood samples and sera were tested for detection of IgG phase II antibodies against C. burnetii by quantitative ELISA. Seroconversion and/or four-fold rise in IgG phase II titers were the diagnostic criteria of acute Q fever infection.
Results: The prevalence of acute Q fever was 5.37% (95% CI: 1.84, 14.61%). Risk factors for Q fever infection included living close to livestock farms and consumption of unpasteurized milk or dairy products. However, these risk factors were not significantly different between patients with Q fever and seronegative cases of Q fever (P<0.612). In current study, 23.21% of the participants were found with a history of Q fever infection.
Conclusion: Acute Q fever was diagnosed in many cases in north of Iran indicating a high prevalence of the disease. Therefore, Q fever serology must be checked in seronegative suspected brucellosis. |
| first_indexed | 2024-04-10T20:31:01Z |
| format | Article |
| id | doaj.art-ae1e362090c14a8abcb3343248cbd36f |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:31:01Z |
| publishDate | 2019-06-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-ae1e362090c14a8abcb3343248cbd36f2023-01-25T06:56:44ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792019-06-0129173100106Epidemiologic Investigation of Acute Q Fever in North of IranRoya Ghasemian0Ehsan Mostafavi1Saber Esmaeili2Sara Arabsheybani3Lotfollah Davoodi4 Associate Professor, Department of Infectious Diseases, Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Department of Epidemiology, National Reference Laboratory of Plague, Tularemia and Q Fever, Pasteur Institute of Iran, Tehran, Iran Assistant Professor, Department of Medical Bacteriology, Faculty of Medical Sciences, Tarbiat Modarres University, Tehran, Iran Infectious Specialist, Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran Assistant Professor, Department of Infectious Diseases, Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: Q fever is a worldwide zoonosis which is an endemic in many regions. Its diagnosis is usually missed especially in human. This research aimed at investigating acute Q fever among suspected patients in northern Iran. Materials and methods: This cross-sectional study was conducted in 56 suspected cases of Q fever selected from 476 febrile patients admitted in Qaemshahr Razi Hospital, Iran 2016, with systemic or respiratory symptoms. Blood samples and sera were tested for detection of IgG phase II antibodies against C. burnetii by quantitative ELISA. Seroconversion and/or four-fold rise in IgG phase II titers were the diagnostic criteria of acute Q fever infection. Results: The prevalence of acute Q fever was 5.37% (95% CI: 1.84, 14.61%). Risk factors for Q fever infection included living close to livestock farms and consumption of unpasteurized milk or dairy products. However, these risk factors were not significantly different between patients with Q fever and seronegative cases of Q fever (P<0.612). In current study, 23.21% of the participants were found with a history of Q fever infection. Conclusion: Acute Q fever was diagnosed in many cases in north of Iran indicating a high prevalence of the disease. Therefore, Q fever serology must be checked in seronegative suspected brucellosis.http://jmums.mazums.ac.ir/article-1-11863-en.htmlq feverdiagnosisiranepidemiology |
| spellingShingle | Roya Ghasemian Ehsan Mostafavi Saber Esmaeili Sara Arabsheybani Lotfollah Davoodi Epidemiologic Investigation of Acute Q Fever in North of Iran Journal of Mazandaran University of Medical Sciences q fever diagnosis iran epidemiology |
| title | Epidemiologic Investigation of Acute Q Fever in North of Iran |
| title_full | Epidemiologic Investigation of Acute Q Fever in North of Iran |
| title_fullStr | Epidemiologic Investigation of Acute Q Fever in North of Iran |
| title_full_unstemmed | Epidemiologic Investigation of Acute Q Fever in North of Iran |
| title_short | Epidemiologic Investigation of Acute Q Fever in North of Iran |
| title_sort | epidemiologic investigation of acute q fever in north of iran |
| topic | q fever diagnosis iran epidemiology |
| url | http://jmums.mazums.ac.ir/article-1-11863-en.html |
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