Juvenile Myoclonic Epilepsy. Update
Juvenile myoclonic epilepsy (JME) is a common disease. However, some aspects of etiology and pathogenesis are not yet fully clarified. This publication describes the development of ideas about JME, the types of seizures that occur in JME, provides a list of triggering factors and a prognosis severit...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2020-07-01
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| Series: | Эпилепсия и пароксизмальные состояния |
| Subjects: | |
| Online Access: | https://www.epilepsia.su/jour/article/view/548 |
| _version_ | 1797879399879540736 |
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| author | I. V. Volkov O. K. Volkova |
| author_facet | I. V. Volkov O. K. Volkova |
| author_sort | I. V. Volkov |
| collection | DOAJ |
| description | Juvenile myoclonic epilepsy (JME) is a common disease. However, some aspects of etiology and pathogenesis are not yet fully clarified. This publication describes the development of ideas about JME, the types of seizures that occur in JME, provides a list of triggering factors and a prognosis severity scale that depending on these triggering factors. The section on JME diagnostics discusses methods of neuroimaging, electroencephalography, and approaches to assessing the mental status of JME patients. The data of meta-analysis of prevalence and risk factors of refractory JME in the context of assessment of the disease state and prognosis are presented. The data on advantages and disadvantages of various Antiepileptic Drugs (AEDs) for the control of the disease are considered. The results of the own study of AED spectrum and effectiveness in gender-sensitive and ILAE-recommended therapy in adults, as well as the GENERAL study of perampanel efficacy and safety in patients with idiopathic generalized epilepsy, are presented. It confirmed the high efficacy of the perampanel primarily for myoclonic seizures and generalized tonic-clonic seizures. A case study of a female patient with JME was also described, in which refractory to therapy was noted, including due to low compliance to the prescribed therapy. |
| first_indexed | 2024-04-10T02:47:00Z |
| format | Article |
| id | doaj.art-ae20e81693a2450d804575fd206fa60d |
| institution | Directory Open Access Journal |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| last_indexed | 2024-04-10T02:47:00Z |
| publishDate | 2020-07-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj.art-ae20e81693a2450d804575fd206fa60d2023-03-13T07:44:17ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882020-07-01121S10.17749/2077-8333.2020.12.1S.S41-S49489Juvenile Myoclonic Epilepsy. UpdateI. V. Volkov0O. K. Volkova1The Novosibirsk City Neurology Center “Sibneiromed”The Novosibirsk City Neurology Center “Sibneiromed”; Novosibirsk Region City Children Emergency Clinical HospitalJuvenile myoclonic epilepsy (JME) is a common disease. However, some aspects of etiology and pathogenesis are not yet fully clarified. This publication describes the development of ideas about JME, the types of seizures that occur in JME, provides a list of triggering factors and a prognosis severity scale that depending on these triggering factors. The section on JME diagnostics discusses methods of neuroimaging, electroencephalography, and approaches to assessing the mental status of JME patients. The data of meta-analysis of prevalence and risk factors of refractory JME in the context of assessment of the disease state and prognosis are presented. The data on advantages and disadvantages of various Antiepileptic Drugs (AEDs) for the control of the disease are considered. The results of the own study of AED spectrum and effectiveness in gender-sensitive and ILAE-recommended therapy in adults, as well as the GENERAL study of perampanel efficacy and safety in patients with idiopathic generalized epilepsy, are presented. It confirmed the high efficacy of the perampanel primarily for myoclonic seizures and generalized tonic-clonic seizures. A case study of a female patient with JME was also described, in which refractory to therapy was noted, including due to low compliance to the prescribed therapy.https://www.epilepsia.su/jour/article/view/548idiopathic generalized epilepsiesigejuvenile myoclonic epilepsyjmemyocloniaantiepileptic drugsaedperampanel |
| spellingShingle | I. V. Volkov O. K. Volkova Juvenile Myoclonic Epilepsy. Update Эпилепсия и пароксизмальные состояния idiopathic generalized epilepsies ige juvenile myoclonic epilepsy jme myoclonia antiepileptic drugs aed perampanel |
| title | Juvenile Myoclonic Epilepsy. Update |
| title_full | Juvenile Myoclonic Epilepsy. Update |
| title_fullStr | Juvenile Myoclonic Epilepsy. Update |
| title_full_unstemmed | Juvenile Myoclonic Epilepsy. Update |
| title_short | Juvenile Myoclonic Epilepsy. Update |
| title_sort | juvenile myoclonic epilepsy update |
| topic | idiopathic generalized epilepsies ige juvenile myoclonic epilepsy jme myoclonia antiepileptic drugs aed perampanel |
| url | https://www.epilepsia.su/jour/article/view/548 |
| work_keys_str_mv | AT ivvolkov juvenilemyoclonicepilepsyupdate AT okvolkova juvenilemyoclonicepilepsyupdate |