Risk Factors of Unfavorable Outcomes, Major Bleeding, and All-Cause Mortality in Patients with Venous Thromboembolism
Purpose: This study aimed to analyze the clinical outcomes of venous thromboembolism (VTE) patients and identify the risk factors for VTE-related unfavorable outcomes, major bleeding, and 30-day all-cause mortality. Materials and Methods : From January 2016 to December 2020, 198 patients with confir...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Medrang
2021-12-01
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| Series: | Vascular Specialist International |
| Subjects: | |
| Online Access: | https://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.210041 |
| _version_ | 1828070748216885248 |
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| author | Han Young Lee Tae Hoon Yeo Tae Kyung Heo Young Gyu Cho Dong Hui Cho Kyung Bok Lee |
| author_facet | Han Young Lee Tae Hoon Yeo Tae Kyung Heo Young Gyu Cho Dong Hui Cho Kyung Bok Lee |
| author_sort | Han Young Lee |
| collection | DOAJ |
| description | Purpose: This study aimed to analyze the clinical outcomes of venous thromboembolism (VTE) patients and identify the risk factors for VTE-related unfavorable outcomes, major bleeding, and 30-day all-cause mortality. Materials and Methods : From January 2016 to December 2020, 198 patients with confirmed VTE were enrolled. Potential risk factors for unfavorable outcomes, major bleeding, and all-cause mortality were analyzed. Results : VTE-related unfavorable outcomes developed in 13.1%, while 30-day all-cause mortality was 8.6%. In the multivariate analysis, a pulse ≥110/min and respiratory rate ≥30/min were statistically significant predictors for VTE-related unfavorable outcomes. Diabetes was a significant risk factor for major bleeding. In addition, a history of malignancy, no anticoagulation treatment, and need for mechanical ventilation were significant predictors of all-cause mortality. Conclusion : VTE-related mortality and morbidity rates remained high. In cases of tachycardia and tachypnea, early aggressive treatment is needed to prevent unfavorable outcomes. Patients with risk factors should be closely monitored. |
| first_indexed | 2024-04-11T00:43:48Z |
| format | Article |
| id | doaj.art-ae21a5ffe60c4f5a9d72fc7dd42c1199 |
| institution | Directory Open Access Journal |
| issn | 2288-7970 2288-7989 |
| language | English |
| last_indexed | 2024-04-11T00:43:48Z |
| publishDate | 2021-12-01 |
| publisher | Medrang |
| record_format | Article |
| series | Vascular Specialist International |
| spelling | doaj.art-ae21a5ffe60c4f5a9d72fc7dd42c11992023-01-06T01:29:53ZengMedrangVascular Specialist International2288-79702288-79892021-12-013710.5758/vsi.210041vsi.210041Risk Factors of Unfavorable Outcomes, Major Bleeding, and All-Cause Mortality in Patients with Venous ThromboembolismHan Young Lee0Tae Hoon Yeo1Tae Kyung Heo2Young Gyu Cho3Dong Hui Cho4Kyung Bok Lee5Department of Surgery, Seoul Medical Center, Seoul, KoreaDepartment of Surgery, Seoul Medical Center, Seoul, KoreaDepartment of Surgery, Seoul Medical Center, Seoul, KoreaDepartment of Surgery, Seoul Medical Center, Seoul, KoreaDepartment of Surgery, Seoul Medical Center, Seoul, KoreaDepartment of Surgery, Dongguk University Ilsan Hospital, Goyang, KoreaPurpose: This study aimed to analyze the clinical outcomes of venous thromboembolism (VTE) patients and identify the risk factors for VTE-related unfavorable outcomes, major bleeding, and 30-day all-cause mortality. Materials and Methods : From January 2016 to December 2020, 198 patients with confirmed VTE were enrolled. Potential risk factors for unfavorable outcomes, major bleeding, and all-cause mortality were analyzed. Results : VTE-related unfavorable outcomes developed in 13.1%, while 30-day all-cause mortality was 8.6%. In the multivariate analysis, a pulse ≥110/min and respiratory rate ≥30/min were statistically significant predictors for VTE-related unfavorable outcomes. Diabetes was a significant risk factor for major bleeding. In addition, a history of malignancy, no anticoagulation treatment, and need for mechanical ventilation were significant predictors of all-cause mortality. Conclusion : VTE-related mortality and morbidity rates remained high. In cases of tachycardia and tachypnea, early aggressive treatment is needed to prevent unfavorable outcomes. Patients with risk factors should be closely monitored.https://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.210041venous thromboembolismrisk factorsmortalityanticoagulants |
| spellingShingle | Han Young Lee Tae Hoon Yeo Tae Kyung Heo Young Gyu Cho Dong Hui Cho Kyung Bok Lee Risk Factors of Unfavorable Outcomes, Major Bleeding, and All-Cause Mortality in Patients with Venous Thromboembolism Vascular Specialist International venous thromboembolism risk factors mortality anticoagulants |
| title | Risk Factors of Unfavorable Outcomes, Major Bleeding, and All-Cause Mortality in Patients with Venous Thromboembolism |
| title_full | Risk Factors of Unfavorable Outcomes, Major Bleeding, and All-Cause Mortality in Patients with Venous Thromboembolism |
| title_fullStr | Risk Factors of Unfavorable Outcomes, Major Bleeding, and All-Cause Mortality in Patients with Venous Thromboembolism |
| title_full_unstemmed | Risk Factors of Unfavorable Outcomes, Major Bleeding, and All-Cause Mortality in Patients with Venous Thromboembolism |
| title_short | Risk Factors of Unfavorable Outcomes, Major Bleeding, and All-Cause Mortality in Patients with Venous Thromboembolism |
| title_sort | risk factors of unfavorable outcomes major bleeding and all cause mortality in patients with venous thromboembolism |
| topic | venous thromboembolism risk factors mortality anticoagulants |
| url | https://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.210041 |
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