Enhanced anti-hepatocarcinoma efficacy by GLUT1 targeting and cellular microenvironment-responsive PAMAM–camptothecin conjugate

Enhanced anti-hepatocarcinoma efficacy by GLUT1 targeting and cellular microenvironment-responsive PAMAM–camptothecin conjugate

The efficient targeting of drugs to tumor cell and subsequent rapid drug release remain primary challenges in the development of nanomedicines for cancer therapy. Here, we constructed a glucose transporter 1 (GLUT1)-targeting and tumor cell microenvironment-sensitive drug release Glucose–PEG–PAMAM-s...

Full description

Bibliographic Details
Main Authors: Pengkai Ma, Yi Sun, Jianhua Chen, Hongpin Li, Hongyu Zhu, Xing Gao, Xinning Bi, Yujie Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
glut1 targeting
tumor microenvironment
pamam dendrimer
conjugate
anticancer drug
Online Access:http://dx.doi.org/10.1080/10717544.2017.1419511

Similar Items

Similar Items