CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers
<p>Abstract</p> <p>Background</p> <p>To investigate the feasibility, and safety of <sup>125</sup>I seed permanent implantation for recurrent head and neck carcinoma under CT-guidance.</p> <p>Results</p> <p>A retrospective study on 14...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-07-01
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| Series: | Radiation Oncology |
| Online Access: | http://www.ro-journal.com/content/5/1/68 |
| _version_ | 1818358711328964608 |
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| author | Liu Chen Yuan Hui SH Jiang Ping Wang Jun J Meng Na Jiang Yu L Qu Ang Yang Rui J |
| author_facet | Liu Chen Yuan Hui SH Jiang Ping Wang Jun J Meng Na Jiang Yu L Qu Ang Yang Rui J |
| author_sort | Liu Chen |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>To investigate the feasibility, and safety of <sup>125</sup>I seed permanent implantation for recurrent head and neck carcinoma under CT-guidance.</p> <p>Results</p> <p>A retrospective study on 14 patients with recurrent head and neck cancers undergone <sup>125</sup>I seed implantation with different seed activities. The post-plan showed that the actuarial D90 of <sup>125</sup>I seeds ranged from 90 to 218 Gy (median, 157.5 Gy). The follow-up was 3 to 60 months (median, 13 months). The median local control was 18 months (95% CI, 6.1-29.9 months), and the 1-, 2-, 3-, and 5- year local controls were 52%, 39%, 39%, and 39%, respectively. The 1-, 2-, 3-, and 5- survival rates were 65%, 39%, 39% and 39%, respectively, with a median survival time of 20 months (95% CI, 8.7-31.3 months). Of all patients, 28.6% (4/14) died of local recurrence, 7.1% (1/14) died of metastases, one patient died of hepatocirrhosis, and 8 patients are still alive to the date of data analysis.</p> <p>Conclusion</p> <p>CT-guided <sup>125</sup>I seed implantation is feasible and safe as a salvage or palliative treatment for patients with recurrent head and neck cancers.</p> |
| first_indexed | 2024-12-13T20:33:20Z |
| format | Article |
| id | doaj.art-ae2b30f336734509a3dff62470081904 |
| institution | Directory Open Access Journal |
| issn | 1748-717X |
| language | English |
| last_indexed | 2024-12-13T20:33:20Z |
| publishDate | 2010-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Radiation Oncology |
| spelling | doaj.art-ae2b30f336734509a3dff624700819042022-12-21T23:32:23ZengBMCRadiation Oncology1748-717X2010-07-01516810.1186/1748-717X-5-68CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancersLiu ChenYuan Hui SHJiang PingWang Jun JMeng NaJiang Yu LQu AngYang Rui J<p>Abstract</p> <p>Background</p> <p>To investigate the feasibility, and safety of <sup>125</sup>I seed permanent implantation for recurrent head and neck carcinoma under CT-guidance.</p> <p>Results</p> <p>A retrospective study on 14 patients with recurrent head and neck cancers undergone <sup>125</sup>I seed implantation with different seed activities. The post-plan showed that the actuarial D90 of <sup>125</sup>I seeds ranged from 90 to 218 Gy (median, 157.5 Gy). The follow-up was 3 to 60 months (median, 13 months). The median local control was 18 months (95% CI, 6.1-29.9 months), and the 1-, 2-, 3-, and 5- year local controls were 52%, 39%, 39%, and 39%, respectively. The 1-, 2-, 3-, and 5- survival rates were 65%, 39%, 39% and 39%, respectively, with a median survival time of 20 months (95% CI, 8.7-31.3 months). Of all patients, 28.6% (4/14) died of local recurrence, 7.1% (1/14) died of metastases, one patient died of hepatocirrhosis, and 8 patients are still alive to the date of data analysis.</p> <p>Conclusion</p> <p>CT-guided <sup>125</sup>I seed implantation is feasible and safe as a salvage or palliative treatment for patients with recurrent head and neck cancers.</p>http://www.ro-journal.com/content/5/1/68 |
| spellingShingle | Liu Chen Yuan Hui SH Jiang Ping Wang Jun J Meng Na Jiang Yu L Qu Ang Yang Rui J CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers Radiation Oncology |
| title | CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers |
| title_full | CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers |
| title_fullStr | CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers |
| title_full_unstemmed | CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers |
| title_short | CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers |
| title_sort | ct guided iodine 125 seed permanent implantation for recurrent head and neck cancers |
| url | http://www.ro-journal.com/content/5/1/68 |
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