Cross-Reactivity Assessment of Vaccine-Derived SARS-CoV-2 T Cell Responses against BA.2.86 and JN.1

Cross-Reactivity Assessment of Vaccine-Derived SARS-CoV-2 T Cell Responses against BA.2.86 and JN.1

The SARS-CoV-2 Omicron sub-variants BA.2.86 and JN.1 contain multiple mutations in the spike protein that were not present in previous variants of concern and Omicron sub-variants. Preliminary research suggests that these variants reduce the neutralizing capability of antibodies induced by vaccines,...

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Bibliographic Details
Main Authors: Muhammad Saqib Sohail, Syed Faraz Ahmed, Ahmed Abdul Quadeer, Matthew R. McKay
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Viruses
Subjects:
SARS-CoV-2
COVID-19
BA.2.86
JN.1
T cell epitopes
immune escape
Online Access:https://www.mdpi.com/1999-4915/16/3/473

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