Characterization of a multipurpose NS3 surface patch coordinating HCV replicase assembly and virion morphogenesis.
The hepatitis C virus (HCV) life cycle is highly regulated and characterized by a step-wise succession of interactions between viral and host cell proteins resulting in the assembly of macromolecular complexes, which catalyse genome replication and/or virus production. Non-structural (NS) protein 3,...
Main Authors: | Olaf Isken, Minh Tu Pham, Hella Schwanke, Felicia Schlotthauer, Ralf Bartenschlager, Norbert Tautz |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-10-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1010895 |
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