Convergent evolution of escape from hepaciviral antagonism in primates.
The ability to mount an interferon response on sensing viral infection is a critical component of mammalian innate immunity. Several viruses directly antagonize viral sensing pathways to block activation of the host immune response. Here, we show that recurrent viral antagonism has shaped the evolut...
Main Authors: | Maulik R Patel, Yueh-Ming Loo, Stacy M Horner, Michael Gale, Harmit S Malik |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC3302847?pdf=render |
Similar Items
-
The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses
by: Lim Efrem S, et al.
Published: (2012-06-01) -
Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G.
by: Sara L Sawyer, et al.
Published: (2004-09-01) -
HIV-1 Escape from Small-Molecule Antagonism of Vif
by: Mark Sharkey, et al.
Published: (2019-02-01) -
Convergent evolution of argonaute-2 slicer antagonism in two distinct insect RNA viruses.
by: Joël T van Mierlo, et al.
Published: (2012-01-01) -
Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates
by: Lei Yang, et al.
Published: (2020-06-01)