| Summary: | Aim of our study was to investigate central motor pathways involvement in children in early recovery period after the aseptic meningitis.Materials and methods: 65 patients (40 children with average age 12 years with aseptic meningitis and 25 age matched controls) were enrolled. TMS (single-pulse protocol) with MEP shape, latency and amplitude and CMCT averaged and analyzed.Results: In aseptic meningitis group in 69–73% of the patients diffuse TMS parameters changes were seen (MEPs amplitudes lowering). These changes may be interpreted as motoneurons diffuse functional activity lowering, but also as a signs of neurodegenerative process of a certain degree. Axonal lesions (MEPs latency lengthening) was registered in 12–15% of the patients of aseptic meningitis group.Conclusion. When aseptic meningitis in most cases, signs of diffuse lesion of motoneurons
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