Changing Survival Rate of Infants Born Before 26 Gestational Weeks : Single-centre study

Objectives: This study aimed to evaluate the changing survival rate and morbidities among infants born before 26 gestational weeks at the Sultan Qaboos University Hospital (SQUH) in Muscat, Oman. Methods: This retrospective study assessed the mortality and morbidities of all premature infants born a...

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Main Authors: Asad Rahman, Mohamed Abdellatif, Sharef W. Sharef, Muhammad Fazalullah, Khalfan Al-Senaidi, Ashfaq A. Khan, Masood Ahmad, Mathew Kripail, Mazen Abuanza, Flordeliza Bataclan
Format: Article
Language:English
Published: Sultan Qaboos University 2015-08-01
Series:Sultan Qaboos University Medical Journal
Subjects:
Online Access:https://journals.squ.edu.om/index.php/squmj/article/view/2042
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author Asad Rahman
Mohamed Abdellatif
Sharef W. Sharef
Muhammad Fazalullah
Khalfan Al-Senaidi
Ashfaq A. Khan
Masood Ahmad
Mathew Kripail
Mazen Abuanza
Flordeliza Bataclan
author_facet Asad Rahman
Mohamed Abdellatif
Sharef W. Sharef
Muhammad Fazalullah
Khalfan Al-Senaidi
Ashfaq A. Khan
Masood Ahmad
Mathew Kripail
Mazen Abuanza
Flordeliza Bataclan
author_sort Asad Rahman
collection DOAJ
description Objectives: This study aimed to evaluate the changing survival rate and morbidities among infants born before 26 gestational weeks at the Sultan Qaboos University Hospital (SQUH) in Muscat, Oman. Methods: This retrospective study assessed the mortality and morbidities of all premature infants born alive at 23–26 gestational weeks at SQUH between June 2006 and May 2013. Infants referred to SQUH within 72 hours of birth during this period were also included. Electronic records were reviewed for gestational age, gender, birth weight, maternal age, mode and place of delivery, antenatal steroid administration, morbidity and outcome. The survival rate was calculated and findings were then compared with those of a previous study conducted in the same hospital from 1991 to 1998. Rates of major morbidities were also calculated. Results: A total of 81 infants between 23–26 gestational weeks were admitted to the neonatal unit during the study period. Of these, 58.0% were male and 42.0% were female. Median gestational age was 25 weeks and mean birth weight was 770 ± 150 g. Of the 81 infants, 49 survived. The overall survival rate was 60.5% compared to 41% reported in the previous study. Respiratory distress syndrome (100.0%), retinopathy of prematurity (51.9%), bronchopulmonary dysplasia (34.6%), intraventricular haemorrhage (30.9%) and patent ductus arteriosus (28.4%) were the most common morbidities. Conclusion: The overall survival rate of infants between 23–26 gestational weeks during the study period had significantly improved in comparison to that found at the same hospital from 1991 to 1998. There is a need for the long-term neurodevelopmental follow-up of premature infants.
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spelling doaj.art-ae3424dfe8ea4d94936283d1db3654d52022-12-22T03:04:43ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282015-08-011533513561962Changing Survival Rate of Infants Born Before 26 Gestational Weeks : Single-centre studyAsad Rahman0Mohamed Abdellatif1Sharef W. Sharef2Muhammad Fazalullah3Khalfan Al-Senaidi4Ashfaq A. Khan5Masood Ahmad6Mathew Kripail7Mazen Abuanza8Flordeliza Bataclan9Department of Child Health, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Child Health, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Child Health, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Child Health, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Child Health, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Child Health, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Child Health, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Child Health, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Child Health, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Child Health, Sultan Qaboos University Hospital, Muscat, OmanObjectives: This study aimed to evaluate the changing survival rate and morbidities among infants born before 26 gestational weeks at the Sultan Qaboos University Hospital (SQUH) in Muscat, Oman. Methods: This retrospective study assessed the mortality and morbidities of all premature infants born alive at 23–26 gestational weeks at SQUH between June 2006 and May 2013. Infants referred to SQUH within 72 hours of birth during this period were also included. Electronic records were reviewed for gestational age, gender, birth weight, maternal age, mode and place of delivery, antenatal steroid administration, morbidity and outcome. The survival rate was calculated and findings were then compared with those of a previous study conducted in the same hospital from 1991 to 1998. Rates of major morbidities were also calculated. Results: A total of 81 infants between 23–26 gestational weeks were admitted to the neonatal unit during the study period. Of these, 58.0% were male and 42.0% were female. Median gestational age was 25 weeks and mean birth weight was 770 ± 150 g. Of the 81 infants, 49 survived. The overall survival rate was 60.5% compared to 41% reported in the previous study. Respiratory distress syndrome (100.0%), retinopathy of prematurity (51.9%), bronchopulmonary dysplasia (34.6%), intraventricular haemorrhage (30.9%) and patent ductus arteriosus (28.4%) were the most common morbidities. Conclusion: The overall survival rate of infants between 23–26 gestational weeks during the study period had significantly improved in comparison to that found at the same hospital from 1991 to 1998. There is a need for the long-term neurodevelopmental follow-up of premature infants.https://journals.squ.edu.om/index.php/squmj/article/view/2042extremely premature infantsneonatessurvival ratemorbidityoman.
spellingShingle Asad Rahman
Mohamed Abdellatif
Sharef W. Sharef
Muhammad Fazalullah
Khalfan Al-Senaidi
Ashfaq A. Khan
Masood Ahmad
Mathew Kripail
Mazen Abuanza
Flordeliza Bataclan
Changing Survival Rate of Infants Born Before 26 Gestational Weeks : Single-centre study
Sultan Qaboos University Medical Journal
extremely premature infants
neonates
survival rate
morbidity
oman.
title Changing Survival Rate of Infants Born Before 26 Gestational Weeks : Single-centre study
title_full Changing Survival Rate of Infants Born Before 26 Gestational Weeks : Single-centre study
title_fullStr Changing Survival Rate of Infants Born Before 26 Gestational Weeks : Single-centre study
title_full_unstemmed Changing Survival Rate of Infants Born Before 26 Gestational Weeks : Single-centre study
title_short Changing Survival Rate of Infants Born Before 26 Gestational Weeks : Single-centre study
title_sort changing survival rate of infants born before 26 gestational weeks single centre study
topic extremely premature infants
neonates
survival rate
morbidity
oman.
url https://journals.squ.edu.om/index.php/squmj/article/view/2042
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