Lens disorders in degenerative myopia. Treatment options

<p> M.G. Rabadanova<sup>1,2</sup>, J.G. Oganezova<sup>1</sup>, E.V. Kremkova<sup>1</sup>, M.M. Yakh'yaeva<sup>1</sup> </p> <p> <sup>1</sup>Pirogov Russian National Research Medical University, Moscow, Russian Feder...

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Main Authors: M.H. Rabadanova, Zh.G. Oganezova, E.V. Kremkova, M.M. Yakh'yaeva
Format: Article
Language:Russian
Published: Prime-Media 2023-11-01
Series:РМЖ "Клиническая офтальмология"
Online Access:http://clinopht.com/upload/iblock/26b/u1i9svh8uljb8me3zwh19linn7do51cg.pdf
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author M.H. Rabadanova
Zh.G. Oganezova
E.V. Kremkova
M.M. Yakh'yaeva
author_facet M.H. Rabadanova
Zh.G. Oganezova
E.V. Kremkova
M.M. Yakh'yaeva
author_sort M.H. Rabadanova
collection DOAJ
description <p> M.G. Rabadanova<sup>1,2</sup>, J.G. Oganezova<sup>1</sup>, E.V. Kremkova<sup>1</sup>, M.M. Yakh'yaeva<sup>1</sup> </p> <p> <sup>1</sup>Pirogov Russian National Research Medical University, Moscow, Russian Federation </p> <p> <sup>2</sup>O.M. Filatov City Clinical Hospital No. 15, Moscow, Russian Federation </p> <p> Cataracts are the leading cause of vision loss in patients over 50 years. In addition to senile cataracts, its earlier development due to various risk factors (for example, degenerative myopia characterized by lens opacity even in low myopia) is also an issue. This article discusses the pathogenesis of cataracts with a focus on oxidative stress, which is also important for myopia progression. The published and authors' data on the association between myopia and cataracts are addressed. The importance of early diagnosis of cataract in patients with myopia at the stage of lens suture compaction and its early radial and meridional opacities (that is possible with maximum mydriasis) is emphasized. Potential complex therapy with anti-cataract drops characterized by antioxidant effect is discussed as a pathogenetic approach to delay cataract progression in patients who (for various reasons) are not suitable for surgery. Recommendations for modifying the lifestyle to prevent cataract development are provided. </p> <p> <b>Keywords:</b> degenerative myopia, myopic cataract, lens, oxidative stress, antioxidants, risk factors, drug treatment, pirenoxine. </p> <p> <b>For citation: </b>Rabadanova M.G., Oganezova J.G., Kremkova E.V., Yakh'yaeva M.M. Lens disorders in degenerative myopia. Treatment options. Russian Journal of Clinical Ophthalmology. 2023;23(4):207–212 (in Russ.). DOI: 10.32364/2311-7729-2023-23-4-6. </p>
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spelling doaj.art-ae37548ba23947589dc52a1f017536572024-02-26T10:12:10ZrusPrime-MediaРМЖ "Клиническая офтальмология"2311-77292619-15712023-11-0123431656Lens disorders in degenerative myopia. Treatment optionsM.H. Rabadanova0Zh.G. Oganezova1E.V. Kremkova2M.M. Yakh'yaeva3Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399<p> M.G. Rabadanova<sup>1,2</sup>, J.G. Oganezova<sup>1</sup>, E.V. Kremkova<sup>1</sup>, M.M. Yakh'yaeva<sup>1</sup> </p> <p> <sup>1</sup>Pirogov Russian National Research Medical University, Moscow, Russian Federation </p> <p> <sup>2</sup>O.M. Filatov City Clinical Hospital No. 15, Moscow, Russian Federation </p> <p> Cataracts are the leading cause of vision loss in patients over 50 years. In addition to senile cataracts, its earlier development due to various risk factors (for example, degenerative myopia characterized by lens opacity even in low myopia) is also an issue. This article discusses the pathogenesis of cataracts with a focus on oxidative stress, which is also important for myopia progression. The published and authors' data on the association between myopia and cataracts are addressed. The importance of early diagnosis of cataract in patients with myopia at the stage of lens suture compaction and its early radial and meridional opacities (that is possible with maximum mydriasis) is emphasized. Potential complex therapy with anti-cataract drops characterized by antioxidant effect is discussed as a pathogenetic approach to delay cataract progression in patients who (for various reasons) are not suitable for surgery. Recommendations for modifying the lifestyle to prevent cataract development are provided. </p> <p> <b>Keywords:</b> degenerative myopia, myopic cataract, lens, oxidative stress, antioxidants, risk factors, drug treatment, pirenoxine. </p> <p> <b>For citation: </b>Rabadanova M.G., Oganezova J.G., Kremkova E.V., Yakh'yaeva M.M. Lens disorders in degenerative myopia. Treatment options. Russian Journal of Clinical Ophthalmology. 2023;23(4):207–212 (in Russ.). DOI: 10.32364/2311-7729-2023-23-4-6. </p>http://clinopht.com/upload/iblock/26b/u1i9svh8uljb8me3zwh19linn7do51cg.pdf
spellingShingle M.H. Rabadanova
Zh.G. Oganezova
E.V. Kremkova
M.M. Yakh'yaeva
Lens disorders in degenerative myopia. Treatment options
РМЖ "Клиническая офтальмология"
title Lens disorders in degenerative myopia. Treatment options
title_full Lens disorders in degenerative myopia. Treatment options
title_fullStr Lens disorders in degenerative myopia. Treatment options
title_full_unstemmed Lens disorders in degenerative myopia. Treatment options
title_short Lens disorders in degenerative myopia. Treatment options
title_sort lens disorders in degenerative myopia treatment options
url http://clinopht.com/upload/iblock/26b/u1i9svh8uljb8me3zwh19linn7do51cg.pdf
work_keys_str_mv AT mhrabadanova lensdisordersindegenerativemyopiatreatmentoptions
AT zhgoganezova lensdisordersindegenerativemyopiatreatmentoptions
AT evkremkova lensdisordersindegenerativemyopiatreatmentoptions
AT mmyakhyaeva lensdisordersindegenerativemyopiatreatmentoptions