Neurological disorder in cattle associated with bovine herpesvirus 4
A nested PCR assay was used to diagnose bovine encephalitis through herpesviruses including bovine herpesvirus 5 (BHV-5), bovine herpesvirus 1 (BHV-1), Aujeszky's disease virus (SHV-1), and ovine herpesvirus 2 (OHV-2) in 14 fragments of central nervous system (CNS) from cattle that died with ne...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Universidade Federal de Minas Gerais
2011-08-01
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| Series: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000400006&lng=en&tlng=en |
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| author | E.A. Costa A.C. Vasconcelos M.R.Q. Bomfim H.B. Amorim G.B.L. Lima F.M. Coelho M. Resende |
| author_facet | E.A. Costa A.C. Vasconcelos M.R.Q. Bomfim H.B. Amorim G.B.L. Lima F.M. Coelho M. Resende |
| author_sort | E.A. Costa |
| collection | DOAJ |
| description | A nested PCR assay was used to diagnose bovine encephalitis through herpesviruses including bovine herpesvirus 5 (BHV-5), bovine herpesvirus 1 (BHV-1), Aujeszky's disease virus (SHV-1), and ovine herpesvirus 2 (OHV-2) in 14 fragments of central nervous system (CNS) from cattle that died with neurological signs. In addition, as some samples of bovine herpesvirus type 4 (BHV-4) have been isolated from neural tissue, it was also tested by nested PCR. The cases of encephalitis occurred in isolation at different times of the year and did not present any seasonality. The duration of the clinical course ranged between 1 to 15 days, and in 64.3% of the cases it manifested between 1 to 2 days. The most frequently observed neurological signs were ataxia, recumbency, unsteadiness and inability to stand, opisthotonus, paddling movements, nystagmus and ptyalism. In the nested assay, there was no evidence of: BHV-1, SHV-1 or OHV-2 in the DNA obtained from the CNS in any of the samples. But the presence of BHV-4 was found in all fragments of the CNS in cattle which died presenting neurological signs. Moreover, BHV-5 was found in association with BHV-4 in two of these samples. |
| first_indexed | 2024-04-13T05:49:54Z |
| format | Article |
| id | doaj.art-ae380820ff5743c3860071ea0e38abe5 |
| institution | Directory Open Access Journal |
| issn | 1678-4162 |
| language | English |
| last_indexed | 2024-04-13T05:49:54Z |
| publishDate | 2011-08-01 |
| publisher | Universidade Federal de Minas Gerais |
| record_format | Article |
| series | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
| spelling | doaj.art-ae380820ff5743c3860071ea0e38abe52022-12-22T02:59:49ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-41622011-08-0163482883510.1590/S0102-09352011000400006S0102-09352011000400006Neurological disorder in cattle associated with bovine herpesvirus 4E.A. Costa0A.C. Vasconcelos1M.R.Q. Bomfim2H.B. Amorim3G.B.L. Lima4F.M. Coelho5M. Resende6Universidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisA nested PCR assay was used to diagnose bovine encephalitis through herpesviruses including bovine herpesvirus 5 (BHV-5), bovine herpesvirus 1 (BHV-1), Aujeszky's disease virus (SHV-1), and ovine herpesvirus 2 (OHV-2) in 14 fragments of central nervous system (CNS) from cattle that died with neurological signs. In addition, as some samples of bovine herpesvirus type 4 (BHV-4) have been isolated from neural tissue, it was also tested by nested PCR. The cases of encephalitis occurred in isolation at different times of the year and did not present any seasonality. The duration of the clinical course ranged between 1 to 15 days, and in 64.3% of the cases it manifested between 1 to 2 days. The most frequently observed neurological signs were ataxia, recumbency, unsteadiness and inability to stand, opisthotonus, paddling movements, nystagmus and ptyalism. In the nested assay, there was no evidence of: BHV-1, SHV-1 or OHV-2 in the DNA obtained from the CNS in any of the samples. But the presence of BHV-4 was found in all fragments of the CNS in cattle which died presenting neurological signs. Moreover, BHV-5 was found in association with BHV-4 in two of these samples.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000400006&lng=en&tlng=enbovinosherpesvírus bovino 4sistema nervoso centrralencefalite |
| spellingShingle | E.A. Costa A.C. Vasconcelos M.R.Q. Bomfim H.B. Amorim G.B.L. Lima F.M. Coelho M. Resende Neurological disorder in cattle associated with bovine herpesvirus 4 Arquivo Brasileiro de Medicina Veterinária e Zootecnia bovinos herpesvírus bovino 4 sistema nervoso centrral encefalite |
| title | Neurological disorder in cattle associated with bovine herpesvirus 4 |
| title_full | Neurological disorder in cattle associated with bovine herpesvirus 4 |
| title_fullStr | Neurological disorder in cattle associated with bovine herpesvirus 4 |
| title_full_unstemmed | Neurological disorder in cattle associated with bovine herpesvirus 4 |
| title_short | Neurological disorder in cattle associated with bovine herpesvirus 4 |
| title_sort | neurological disorder in cattle associated with bovine herpesvirus 4 |
| topic | bovinos herpesvírus bovino 4 sistema nervoso centrral encefalite |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000400006&lng=en&tlng=en |
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