Comparison of the thinnest corneal thickness measured by Sirius, Oculyzer, AS-OCT and A-mode ultrasonography in myopic patients

AIM:To compare the difference, correlation and consistency of the thinnest corneal thickness(TCT)in myopic patients among Sirius, Oculyzer, anterior segment optical coherence tomography(AS-OCT)and A-mode ultrasound pachymetry, in order to provide a reference for clinical applications.<p>METHOD...

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Main Authors: Yu-Hui Duan, Sheng-Jian Mi, Zhong-Ji Li, Wei Gao
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2019-08-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2019/8/201908026.pdf
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author Yu-Hui Duan
Sheng-Jian Mi
Zhong-Ji Li
Wei Gao
author_facet Yu-Hui Duan
Sheng-Jian Mi
Zhong-Ji Li
Wei Gao
author_sort Yu-Hui Duan
collection DOAJ
description AIM:To compare the difference, correlation and consistency of the thinnest corneal thickness(TCT)in myopic patients among Sirius, Oculyzer, anterior segment optical coherence tomography(AS-OCT)and A-mode ultrasound pachymetry, in order to provide a reference for clinical applications.<p>METHODS: TCT was measured in 81 patients(162 eyes)treated between March and April, 2016 using Sirius, Oculyzer, AS-OCT and A-mode ultrasound pachymetry before femtosecond LASIK, and then the values were statistically analyzed.<p>RESULTS: TCT measured by A-mode ultrasound pachymetry, Sirius, Oculyzerand AS-OCT were respectively(537.91±24.12)μm,(538.12±22.64)μm,(538.20±23.74)μm,(527.04±23.11)μm(<i>P</i><0.01). There was a significant difference in TCT measurements among the four measurements. The results of AS-OCT were significantly smaller than those of the other three methods. There was no statistical difference among A-mode ultrasound pachymetry, Sirius and Oculyzer.Pearson correlation coefficient of measured value by the four measurements were more than 0.9(<i>r</i>=0.920, 0.914, 0.951, 0.908, 0.929, 0.919, <i>P</i><0.001), which means there were highly correlation between each other. The 95% <i>CI</i> of the consistency interval of A-mode ultrasound pachymetry and Sirius, A-mode ultrasound pachymetry and Oculyzer, A-mode ultrasound pachymetry and AS-OCT were(-18.77-18.33)μm,(-19.79-19.19)μm,(-3.79-25.53)μm, respectively. The Bland-Altman Plots demonstrates relatively good consistency between A-mode ultrasound pachymetry and the other three methods.<p>CONCLUSION:The TCT measured by AS-OCT were thinner than that measured by A-mode ultrasound pachymetry. There were a high correlation and consistency of the thinnest corneal thickness in myopic patients among Sirius, Oculyzer, AS-OCT and A-mode ultrasound pachymetry. The TCT measured by the four measurements can be referenced but not replaced since the 95% of the consistency intervals were wide.
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spelling doaj.art-ae3ede8ffb7240fb98c2ee2547f0857a2022-12-21T17:00:46ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232019-08-011981377138010.3980/j.issn.1672-5123.2019.8.26Comparison of the thinnest corneal thickness measured by Sirius, Oculyzer, AS-OCT and A-mode ultrasonography in myopic patientsYu-Hui Duan0Sheng-Jian Mi1Zhong-Ji Li2Wei Gao3Department of Ophthalmology, the Armed Police Corps Hospital in Shaanxi Province, Xi'an 710054, Shaanxi Province, ChinaDepartment of Ophthalmology, the Armed Police Corps Hospital in Shaanxi Province, Xi'an 710054, Shaanxi Province, ChinaDepartment of Ophthalmology, the Armed Police Corps Hospital in Shaanxi Province, Xi'an 710054, Shaanxi Province, ChinaDepartment of Ophthalmology, the Armed Police Corps Hospital in Shaanxi Province, Xi'an 710054, Shaanxi Province, ChinaAIM:To compare the difference, correlation and consistency of the thinnest corneal thickness(TCT)in myopic patients among Sirius, Oculyzer, anterior segment optical coherence tomography(AS-OCT)and A-mode ultrasound pachymetry, in order to provide a reference for clinical applications.<p>METHODS: TCT was measured in 81 patients(162 eyes)treated between March and April, 2016 using Sirius, Oculyzer, AS-OCT and A-mode ultrasound pachymetry before femtosecond LASIK, and then the values were statistically analyzed.<p>RESULTS: TCT measured by A-mode ultrasound pachymetry, Sirius, Oculyzerand AS-OCT were respectively(537.91±24.12)μm,(538.12±22.64)μm,(538.20±23.74)μm,(527.04±23.11)μm(<i>P</i><0.01). There was a significant difference in TCT measurements among the four measurements. The results of AS-OCT were significantly smaller than those of the other three methods. There was no statistical difference among A-mode ultrasound pachymetry, Sirius and Oculyzer.Pearson correlation coefficient of measured value by the four measurements were more than 0.9(<i>r</i>=0.920, 0.914, 0.951, 0.908, 0.929, 0.919, <i>P</i><0.001), which means there were highly correlation between each other. The 95% <i>CI</i> of the consistency interval of A-mode ultrasound pachymetry and Sirius, A-mode ultrasound pachymetry and Oculyzer, A-mode ultrasound pachymetry and AS-OCT were(-18.77-18.33)μm,(-19.79-19.19)μm,(-3.79-25.53)μm, respectively. The Bland-Altman Plots demonstrates relatively good consistency between A-mode ultrasound pachymetry and the other three methods.<p>CONCLUSION:The TCT measured by AS-OCT were thinner than that measured by A-mode ultrasound pachymetry. There were a high correlation and consistency of the thinnest corneal thickness in myopic patients among Sirius, Oculyzer, AS-OCT and A-mode ultrasound pachymetry. The TCT measured by the four measurements can be referenced but not replaced since the 95% of the consistency intervals were wide.http://ies.ijo.cn/cn_publish/2019/8/201908026.pdfSiriusOculyzeranterior segment optical coherence tomographyA-mode ultrasound pachymetrythinnest corneal thickness
spellingShingle Yu-Hui Duan
Sheng-Jian Mi
Zhong-Ji Li
Wei Gao
Comparison of the thinnest corneal thickness measured by Sirius, Oculyzer, AS-OCT and A-mode ultrasonography in myopic patients
Guoji Yanke Zazhi
Sirius
Oculyzer
anterior segment optical coherence tomography
A-mode ultrasound pachymetry
thinnest corneal thickness
title Comparison of the thinnest corneal thickness measured by Sirius, Oculyzer, AS-OCT and A-mode ultrasonography in myopic patients
title_full Comparison of the thinnest corneal thickness measured by Sirius, Oculyzer, AS-OCT and A-mode ultrasonography in myopic patients
title_fullStr Comparison of the thinnest corneal thickness measured by Sirius, Oculyzer, AS-OCT and A-mode ultrasonography in myopic patients
title_full_unstemmed Comparison of the thinnest corneal thickness measured by Sirius, Oculyzer, AS-OCT and A-mode ultrasonography in myopic patients
title_short Comparison of the thinnest corneal thickness measured by Sirius, Oculyzer, AS-OCT and A-mode ultrasonography in myopic patients
title_sort comparison of the thinnest corneal thickness measured by sirius oculyzer as oct and a mode ultrasonography in myopic patients
topic Sirius
Oculyzer
anterior segment optical coherence tomography
A-mode ultrasound pachymetry
thinnest corneal thickness
url http://ies.ijo.cn/cn_publish/2019/8/201908026.pdf
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