Cutaneous diffuse large B-cell lymphoma, leg type - a typical case

Cutaneous diffuse large B-cell lymphoma, leg type, is a rare, aggressive, and poorly prognostic neoplasm. It corresponds to 10-20% of cutaneous B-cell lymphomas and mainly affects the lower limbs of older women. We report the case of an 81-year-old woman with painful, fast-growing nodules and tumors...

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Main Authors: Flávia Regina Ferreira, Mariana Oliveira Fernandes, Marina Thereza Fogo Pereira, Fernanda da Rocha Gonçalves
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia (SBD) 2022-12-01
Series:Surgical & Cosmetic Dermatology
Subjects:
Online Access:http://www.surgicalcosmetic.org.br/Content/imagebank/pdf/v14/en_v14a65.pdf
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author Flávia Regina Ferreira
Mariana Oliveira Fernandes
Marina Thereza Fogo Pereira
Fernanda da Rocha Gonçalves
author_facet Flávia Regina Ferreira
Mariana Oliveira Fernandes
Marina Thereza Fogo Pereira
Fernanda da Rocha Gonçalves
author_sort Flávia Regina Ferreira
collection DOAJ
description Cutaneous diffuse large B-cell lymphoma, leg type, is a rare, aggressive, and poorly prognostic neoplasm. It corresponds to 10-20% of cutaneous B-cell lymphomas and mainly affects the lower limbs of older women. We report the case of an 81-year-old woman with painful, fast-growing nodules and tumors in her left leg. Histopathological and immunohistochemical findings, associated with the absence of extra-cutaneous involvement during staging, concluded the diagnosis of cutaneous diffuse large B-cell lymphoma, leg type. The rarity of this limphoma, its typical clinic and epidemiology, and the excellent response to treatment motivated this report.
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spelling doaj.art-ae42b288be174e89ae9d8bd6c61df9782023-02-02T19:25:29ZengSociedade Brasileira de Dermatologia (SBD)Surgical & Cosmetic Dermatology1984-87732022-12-011410.5935/scd1984-8773.2022140065Cutaneous diffuse large B-cell lymphoma, leg type - a typical caseFlávia Regina Ferreira0Mariana Oliveira Fernandes1Marina Thereza Fogo Pereira2Fernanda da Rocha Gonçalves3Hospital Municipal Universitário de Taubaté, Dermatology Service, Taubaté (SP), Brazil.Hospital Municipal Universitário de Taubaté, Dermatology Service, Taubaté (SP), Brazil.Hospital Municipal Universitário de Taubaté, Dermatology Service, Taubaté (SP), Brazil.Hospital do Servidor Público Estadual, Pathology, São Paulo (SP), Brazil.Cutaneous diffuse large B-cell lymphoma, leg type, is a rare, aggressive, and poorly prognostic neoplasm. It corresponds to 10-20% of cutaneous B-cell lymphomas and mainly affects the lower limbs of older women. We report the case of an 81-year-old woman with painful, fast-growing nodules and tumors in her left leg. Histopathological and immunohistochemical findings, associated with the absence of extra-cutaneous involvement during staging, concluded the diagnosis of cutaneous diffuse large B-cell lymphoma, leg type. The rarity of this limphoma, its typical clinic and epidemiology, and the excellent response to treatment motivated this report.http://www.surgicalcosmetic.org.br/Content/imagebank/pdf/v14/en_v14a65.pdfimmunohistochemistrydiffuselymphoma non hodgkinlymphoma large b-cellneoplasmstherapeutics
spellingShingle Flávia Regina Ferreira
Mariana Oliveira Fernandes
Marina Thereza Fogo Pereira
Fernanda da Rocha Gonçalves
Cutaneous diffuse large B-cell lymphoma, leg type - a typical case
Surgical & Cosmetic Dermatology
immunohistochemistry
diffuse
lymphoma non hodgkin
lymphoma large b-cell
neoplasms
therapeutics
title Cutaneous diffuse large B-cell lymphoma, leg type - a typical case
title_full Cutaneous diffuse large B-cell lymphoma, leg type - a typical case
title_fullStr Cutaneous diffuse large B-cell lymphoma, leg type - a typical case
title_full_unstemmed Cutaneous diffuse large B-cell lymphoma, leg type - a typical case
title_short Cutaneous diffuse large B-cell lymphoma, leg type - a typical case
title_sort cutaneous diffuse large b cell lymphoma leg type a typical case
topic immunohistochemistry
diffuse
lymphoma non hodgkin
lymphoma large b-cell
neoplasms
therapeutics
url http://www.surgicalcosmetic.org.br/Content/imagebank/pdf/v14/en_v14a65.pdf
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AT marianaoliveirafernandes cutaneousdiffuselargebcelllymphomalegtypeatypicalcase
AT marinatherezafogopereira cutaneousdiffuselargebcelllymphomalegtypeatypicalcase
AT fernandadarochagoncalves cutaneousdiffuselargebcelllymphomalegtypeatypicalcase